product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-CD79b Antibody
catalog :
PB9169
quantity :
100 ug/vial
price :
240 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
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product information
Product Name :
Anti-CD79b Antibody
Catalog Number :
PB9169
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for B-cell antigen receptor complex-associated protein beta chain(CD79B) detection. Tested with WB, IHC-P, ICC in Human;Mouse;Rat.
Price :
240 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human, mouse, rat
Applications :
WB,IHC-P,ICC
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human
Immunohistochemistry(Paraffin-embedded S ... :
Concentration: 0.5-1μg/ml; Tested Species: Human, Mouse, Rat
Immunohistochemistry(Frozen Section) :
Concentration: 0.5-1μg/ml; Tested Species: Human
Notes :
WB: The detection limit for CD79b is approximately 0.25ng/lane under reducing conditions.
Tested Species: In-house tested species with positive results.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Immunogen :
E.coli-derived human CD79b recombinant protein (Position: A29-E229). Human CD79b shares 70% amino acid (aa) sequence identity with mouse CD79b.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P) and ICC.
Background :
CD79b molecule, immunoglobulin-associated beta, also known as CD79B (Cluster of Differentiation 79B), is a human gene. By fluorescence in situ hybridization, It is mapped to 17q23.3. The CD79B protein together with the related CD79A protein, forms a dimer associated with membrane bound immunoglobulin in B-cells, thus forming the B-cell antigen receptor (BCR) which is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). CD79b also can enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
Reference :
1. "Entrez Gene: CD79B CD79b molecule, immunoglobulin-associated beta"
2. Dobbs, A. K., Yang, T., Farmer, D., Kager, L., Parolini, O., Conley, M. E. Cutting edge: a hypomorphic mutation in Ig-beta (CD79b) in a patient with immunodeficiency and a leaky defect in B cell development. J. Immun. 179: 2055-2059, 2007.
3. Wood, W. J., Jr., Thompson, A. A., Korenberg, J., Chen, X., May, W., Wall, R., Denny, C. T. Isolation and chromosomal mapping of the human immunoglobulin-associated B29 gene (IGB). Genomics 16: 187-192, 1993.
Gene Name :
CD79B
Protein Name :
B-cell antigen receptor complex-associated protein beta chain
Gene Full Name :
CD79b molecule, immunoglobulin-associated beta
Synonyms :
AGM6 antibody B cell antigen receptor complex associated protein beta chain antibody B cell specific glycoprotein B29 antibody B-cell antigen receptor complex-associated protein beta chain antibody B-cell-specific glycoprotein B29 antibody B29 antibody B29/Ig-beta/CD79b antibody CD 79b antibody CD79b antibody CD79b antigen (immunoglobulin associated beta) antibody CD79b antigen antibody CD79b molecule antibody CD79b molecule immunoglobulin associated beta antibody CD79b protein antibody CD79B_HUMAN antibody Ig beta antibody Ig-beta antibody IGB antibody Igbeta antibody Immunoglobulin associated B29 antibody Immunoglobulin associated B29 protein antibody Immunoglobulin associated beta antibody Immunoglobulin associated protein antibody Immunoglobulin-associated B29 protein antibody MGC108607 antibody
Uniprot ID :
P40259
more info or order :
company information

Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com925.485.4527
headquarters: USA
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