Anti-CD79a Antibody | Boster Immunoleader PB9168 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-CD79a Antibody

catalog :

PB9168

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

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product information

Product Name :

Anti-CD79a Antibody

Catalog Number :

PB9168

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for B-cell antigen receptor complex-associated protein alpha chain(CD79A) detection. Tested with WB, IHC-P, ICC in Human;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat

Applications :

WB,IHC-P,ICC

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human

Immunohistochemistry(Frozen Section) :

Concentration: 0.5-1μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human CD79a recombinant protein (Position: T121-P226). Human CD79a shares 91% amino acid (aa) sequence identity with mouse CD79a.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P) and ICC.

Background :

Cluster of differentiation CD79A also known as B-cell antigen receptor complex-associated protein alpha chain and MB-1 membrane glycoprotein, is a protein that in humans is encoded by the CD79A gene. It is mapped to 19q13.2. CD79A is a membrane protein with an extracellular immunoglobulin domain, a single span transmembrane region and a short cytoplasmic domain. Genetic deletion of the transmembrane exon of CD79A results in loss of CD79A protein and a complete block of B cell development at the pro to pre B cell transition. Similarly, humans with homozygous splice variants in CD79A predicted to result in loss of the transmembrane region and a truncated or absent protein display agammaglobulinemia and no peripheral B cells.

Reference :

1. Pelanda R, Braun U, Hobeika E, Nussenzweig MC, Reth M (2002). "B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta". J. Immunol. 169 (2): 865–72. 2. Minegishi Y, Coustan-Smith E, Rapalus L, Ersoy F, Campana D, Conley ME (1999). "Mutations in Igalpha (CD79a) result in a complete block in B-cell development.". The Journal of Clinical Investigation 104 (8): 1115–21. 3. Wang Y, Kanegane H, Sanal O, Tezcan I, Ersoy F, Futatani T, Miyawaki T (2002). "Novel Ig a (CD79a) gene mutation in a Turkish patient with B cell-deficient agammaglobulinemia". American Journal of Medical Genetics 336: 333–336.

Gene Name :

CD79A

Protein Name :

B-cell antigen receptor complex-associated protein alpha chain

Gene Full Name :

CD79a molecule, immunoglobulin-associated alpha

Synonyms :

B cell antigen receptor complex associated protein alpha chain antibody B cell antigen receptor complex associated protein alpha chain precursor antibody B Lymphocyte Specific MB1 Protein antibody B lymphocyte-specific MB1 protein antibody B-cell antigen receptor complex-associated protein alpha chain antibody CD 79a antibody CD79a antibody CD79a antigen (immunoglobulin-associated alpha) antibody CD79A antigen antibody CD79A antigen immunoglobulin associated alpha antibody CD79a molecule immunoglobulin associated alpha antibody CD79a molecule, immunoglobulin-associated alpha antibody CD79A_HUMAN antibody Ig alpha antibody Ig-alpha antibody IGA antibody IgM-alpha antibody Immunoglobulin Associated Alpha antibody Immunoglobulin-associated alpha antibody Ly54 antibody MB 1 antibody MB 1 membrane glycoprotein antibody MB-1 membrane glycoprotein antibody MB1 antibody MB1 membrane glycoprotein antibody Membrane bound immunoglobulin associated protein antibody Membrane-bound immunoglobulin-associated protein antibody Surface IgM associated protein antibody Surface IgM-associated protein antibody

Uniprot ID :

P11912

more info or order :

Boster Immunoleader product webpage