Boster Immunoleader

antibody

Anti-SIRT3 Antibody

PB9161

100 ug/vial

240 USD

polyclonal

rabbit

human, rat

Anti-SIRT3 Antibody

PB9161

Polyclonal

Rabbit IgG polyclonal antibody for NAD-dependent protein deacetylase sirtuin-3, mitochondrial(SIRT3) detection. Tested with WB in Human;Rat.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, rat

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

WB: The detection limit for SIRT3 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

E.coli-derived human SIRT3 recombinant protein (Position: P66-K399). Human SIRT3 shares 86% amino acid (aa) sequence identity with mouse SIRT3.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

NAD-dependent deacetylase sirtuin-3, mitochondrial also known as SIRT3 is a protein that in humans is encoded by the SIRT3 gene. SIRT3 is member of the mammalian sirtuin family of proteins, which are homologs to the yeast Sir2 protein. It is mapped to 11p15.5. Endogenous SIRT3 is a soluble protein located in the mitochondrial matrix. Overexpression of SIRT3 in cultured cells increases respiration and decreases the production of reactive oxygen species. SIRT3 can function as a mitochondrial deacetylase. In addition to it, human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.

1. "Entrez Gene: SIRT3 sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)" 2. Schwer B, North BJ, Frye RA, Ott M, Verdin E (August 2002). "The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase". J. Cell Biol. 158 (4): 647–57. 3. Onyango P, Celic I, McCaffery JM, Boeke JD, Feinberg AP (October 2002). "SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria". Proc. Natl. Acad. Sci. U.S.A. 99 (21): 13653–8.

SIRT3

NAD-dependent protein deacetylase sirtuin-3, mitochondrial

sirtuin 3

hSIRT 3 antibody hSIRT3 antibody Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase antibody NAD dependent deacetylase sirtuin 3 mitochondrial antibody NAD-dependent protein deacetylase sirtuin-3, mitochondrial antibody Regulatory protein SIR2 homolog 3 antibody Silent mating type information regulation 2 S.cerevisiae homolog 3 antibody Sir 2 like 3 antibody SIR 2 like protein 3 antibody SIR 3 antibody SIR2 L3 antibody Sir2 like 3 antibody SIR2 like protein 3 antibody SIR2-like protein 3 antibody SIR2L3 antibody SIR3_HUMAN antibody SIRT 3 antibody SIRT3 antibody Sirtuin 3 antibody Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae) antibody Sirtuin type 3 antibody Sirtuin3 antibody

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