Boster Immunoleader

antibody

Anti-CD18 Antibody

PB9141

100 ug/vial

240 USD

polyclonal

rabbit

western blot, immunocytochemistry, immunohistochemistry - paraffin section

info changed 20150409

Anti-CD18 Antibody

PB9141

Polyclonal

Rabbit IgG polyclonal antibody for Integrin beta-2(ITGB2) detection. Tested with WB, IHC-P, ICC in Human.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB,IHC-P,ICC

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Concentration: 0.5-1μg/ml; Tested Species: Human

Concentration: 0.5-1μg/ml; Tested Species: Human

WB: The detection limit for CD18 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

E.coli-derived human CD18 recombinant protein (Position: Q404-S769). Human CD18 shares 76% amino acid (aa) sequence identity with mouse CD18.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P) and ICC.

ITGB2(INTEGRIN, BETA-2), also known as CD18, is a protein that in humans is encoded by the ITGB2 gene. ITGB2 is an integrin protein that belongs to the class of cell membrane glycoproteins. The beta-2 integrin chain gene is designated ITGB2 and the leukocyte antigen has been designated CD18. The ITGB2 gene is mapped to 21q22.3. The expression of CD18 is increased in lymphoblastoid cells from persons with Down syndrome, consistent with the location of the gene on chromosome 21. In humans lack of ITGB2 causes Leukocyte Adhesion Deficiency, a disease defined by a lack of leukocyte extravasation from blood into tissues. Although ITGB2 is expressed on the cell surface at normal levels and is capable of function following extracellular stimulation, it could not be activated via the 'inside-out' signaling pathways.

1. Abramson, J. S., Mills, E. L., Sawyer, M. K., Regelmann, W. R., Nelson, J. D., Quie, P. G. Recurrent infections and delayed separation of the umbilical cord in an infant with abnormal phagocytic cell locomotion and oxidative response during particle phagocytosis. J. Pediat. 99: 887-894, 1981. 2. Akao, Y., Utsumi, K. R., Naito, K., Ueda, R., Takahashi, T., Yamada, K. Chromosomal assignments of genes coding for human leukocyte common antigen, T-200, and lymphocyte function-associated antigen 1, LFA-1 beta subunit. Somat. Cell Molec. Genet. 13: 273-278, 1987. 3. "Entrez Gene: ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

ITGB2

Integrin beta-2

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

95 subunit beta antibody Beta 2 (antigen CD18 (p95) antibody CD 18 antibody CD18 antibody CD18 antigen antibody Cell surface adhesion glycoprotein LFA 1/CR3/P150,959 beta subunit precursor) antibody Cell surface adhesion glycoproteins LFA 1/CR3/p150 95 subunit beta antibody Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta antibody Cell surface adhesion glycoproteins LFA 1/CR3/p15095 beta subunit antibody Cell surface adhesion glycoproteins LFA-1/CR3/p150 antibody Complement component 3 receptor 3 and 4 subunit antibody Complement receptor C3 beta subunit antibody Complement receptor C3 subunit beta antibody Integrin beta 2 antibody Integrin beta chain beta 2 antibody Integrin beta-2 antibody Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) antibody ITB2_HUMAN antibody ITGB 2 antibody ITGB2 antibody LAD antibody LCAMB antibody Leukocyte associated antigens CD18/11A, CD18/11B, CD18/11C antibody Leukocyte Cell Adhesion Molecule CD18 antibody LFA 1 antibody LFA1 antibody Lymphocyte function associated antigen 1 antibody MAC 1 antibody MAC1 antibody Macrophage antigen 1 (mac1) beta subunit antibody MF17 antibody MFI7 antibody OTTHUMP00000115278 antibody OTTHUMP00000115279 antibody OTTHUMP00000115280 antibody OTTHUMP00000115281 antibody OTTHUMP00000115282 antibody

P05107