Anti-SynCAM Antibody | Boster Immunoleader PB9136 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-SynCAM Antibody

catalog :

PB9136

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-SynCAM Antibody

Catalog Number :

PB9136

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Cell adhesion molecule 1(CADM1) detection. Tested with WB in Human;Mouse;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, mouse, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse, Rat

Notes :

WB: The detection limit for SynCAM is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human SynCAM recombinant protein (Position: Q45-P340). Human SynCAM shares 99% amino acid (aa) sequence identity with mouse SynCAM.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Cell adhesion molecule 1 is a protein that, in humans, is encoded by the CADM1 gene. This gene is also known as IGSF4, SYNCAM or TSLC1, and it is mapped to 11q23.3. CADM1 functions as a homophilic cell adhesion molecule at the synapse. Expression of the isolated cytoplasmic tail of CADM1 in neurons inhibited synapse assembly. Conversely, expression of full-length CADM1 in nonneuronal cells induced synapse formation by cocultured hippocampal neurons with normal release properties.

Reference :

1. Biederer, T., Sara, Y., Mozhayeva, M., Atasoy, D., Liu, X., Kavalali, E. T., Sudhof, T. C.SynCAM, a synaptic adhesion molecule that drives synapse assembly. Science 297: 1525-1531, 2002. 2. Gomyo H, Arai Y, Tanigami A, Murakami Y, Hattori M, Hosoda F, Arai K, Aikawa Y, Tsuda H, Hirohashi S, Asakawa S, Shimizu N, Soeda E, Sakaki Y, Ohki M (Feb 2000). "A 2-Mb sequence-ready contig map and a novel immunoglobulin superfamily gene IGSF4 in the LOH region of chromosome 11q23.2". Genomics 62 (2): 139–46. 3. Yageta, Mika; Kuramochi Masami, Masuda Mari, Fukami Takeshi, Fukuhara Hiroshi, Maruyama Tomoko, Shibuya Masabumi, Murakami Yoshinori (Sep 2002). "Direct association of TSLC1 and DAL-1, two distinct tumor suppressor proteins in lung cancer". Cancer Res. (United States) 62 (18): 5129–33.

Gene Name :

CADM1

Protein Name :

Cell adhesion molecule 1

Gene Full Name :

cell adhesion molecule 1

Synonyms :

BL2 antibody Cadm1 antibody CADM1_HUMAN antibody Cell adhesion molecule 1 antibody DKFZp686F1789 antibody IgSF4 antibody IGSF4A antibody Immunoglobulin superfamily member 4 antibody MGC149785 antibody MGC51880 antibody NECL-2 antibody NECL2 antibody Nectin like 2 antibody Nectin-like protein 2 antibody RA175 antibody SgIGSF antibody Spermatogenic immunoglobulin superfamily antibody ST17 antibody sTSLC 1 antibody Synaptic cell adhesion molecule antibody SynCAM antibody SynCAM1 antibody TSLC-1 antibody TSLC1 antibody Tumor suppressor in lung cancer 1 antibody

Uniprot ID :

Q9BY67

more info or order :

Boster Immunoleader product webpage