product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-ATF2 Antibody
catalog :
PB9131
quantity :
100 ug/vial
price :
240 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
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product information
Product Name :
Anti-ATF2 Antibody
Catalog Number :
PB9131
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Cyclic AMP-dependent transcription factor ATF-2(ATF2) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
Price :
240 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human, mouse, rat
Applications :
WB,IHC-P,IHC-F
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat
Immunohistochemistry(Paraffin-embedded S ... :
Concentration: 0.5-1μg/ml; Tested Species: Human, Mouse, Rat
Immunohistochemistry(Frozen Section) :
Concentration: 0.5-1μg/ml; Tested Species: Rat
Notes :
WB: The detection limit for ATF2 is approximately 0.25ng/lane under reducing conditions.
Tested Species: In-house tested species with positive results.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Immunogen :
E.coli-derived human ATF2 recombinant protein (Position: E93-E450). Human ATF2 shares 99% amino acid (aa) sequence identity with both mouse and rat ATF2.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P) and IHC(F).
Background :
ATF2, also known as Activating transcription factor 2, is a protein that in humans is encoded by the ATF2 gene. It is mapped to 2q31.1. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA-binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus, it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.
Reference :
1. "Entrez Gene: ATF2 activating transcription factor 2"
2. Bhoumik A, Takahashi S, Breitweiser W, Shiloh Y, Jones N, Ronai Z (May 2005). "ATM-dependent phosphorylation of ATF2 is required for the DNA damage response". Mol. Cell 18 (5): 577–87.
Gene Name :
ATF2
Protein Name :
Cyclic AMP-dependent transcription factor ATF-2
Gene Full Name :
activating transcription factor 2
Synonyms :
Activating Transcription Factor 2 antibody Activating transcription factor 2 splice variant ATF2 var2 antibody ATF 2 antibody Atf-2 antibody Atf2 antibody ATF2 protein antibody ATF2_HUMAN antibody cAMP Response Element Binding Protein 2 antibody cAMP response element binding protein CRE BP1 antibody cAMP response element-binding protein CRE-BP1 antibody cAMP responsive element binding protein 2, formerly antibody cAMP-dependent transcription factor ATF-2 antibody cAMP-responsive element-binding protein 2 antibody CRE BP1 antibody CRE-BP antibody CREB 2 antibody CREB-2 antibody CREB2 antibody CREBP1 antibody Cyclic AMP dependent transcription factor ATF 2 antibody Cyclic AMP-dependent transcription factor ATF-2 antibody Cyclic AMP-responsive element-binding protein 2 antibody D130078H02Rik antibody D18875 antibody HB 16 antibody HB16 antibody Histone acetyltransferase ATF2 antibody MGC105211 antibody MGC105222 antibody MGC111558 antibody MGC142504 antibody mXBP antibody MXBP protein antibody Tg(Gzma-Klra1)7Wum antibody TREB 7 antibody TREB7 antibody
Uniprot ID :
P15336
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company information

Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com925.485.4527
headquarters: USA
Premium Provider of Antibodies and ELISA Kits
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