Boster Immunoleader

antibody

Anti-ATF1 Antibody

PB9130

100 ug/vial

240 USD

polyclonal

rabbit

human, rat

western blot, immunohistochemistry - paraffin section

Anti-ATF1 Antibody

PB9130

Polyclonal

Rabbit IgG polyclonal antibody for Cyclic AMP-dependent transcription factor ATF-1(ATF1) detection. Tested with WB, IHC-P in Human;Rat.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, rat

WB,IHC-P

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

Concentration: 0.5-1μg/ml; Tested Species: Human

WB: The detection limit for ATF1 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

E.coli-derived human ATF1 recombinant protein (Position: M1-V271). Human ATF1 shares 91% amino acid (aa) sequence identity with mouse ATF1.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

ATF1, also known as activating transcription factor 1, is a protein that in humans is encoded by the ATF1 gene. It is mapped to 12q13.12. This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation.

1. ucman, J., Delattre, O., Desmaze, C., Epstein, A. L., Stenman, G., Speleman, F., Fletchers, C. D. M., Aurias, A., Thomas, G. EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts. Nature Genet. 4: 341-345, 1993. 2. "Entrez Gene: ATF1 activating transcription factor 1

ATF1

Cyclic AMP-dependent transcription factor ATF-1

activating transcription factor 1

Activating transcription factor 1 antibody ATF 1 antibody atf1 antibody ATF1 EWS fusion gene antibody ATF1 FUS fusion gene antibody ATF1_HUMAN antibody cAMP dependent transcription factor 1 antibody cAMP-dependent transcription factor ATF-1 antibody Cyclic AMP dependent transcription factor ATF 1 antibody Cyclic AMP dependent transcription factor ATF1 antibody Cyclic AMP-dependent transcription factor ATF-1 antibody EWS AFT1 antibody FUS ATF 1 antibody FUS/ATF 1 antibody Protein TREB36 antibody RNA binding protein activating transcription factor 1 fusion protein antibody TREB 36 antibody TREB36 antibody TREB36 protein antibody

P18846