Boster Immunoleader

antibody

Anti-AP2 alpha Antibody

PB9118

100 ug/vial

240 USD

polyclonal

rabbit

human, rat

Anti-AP2 alpha Antibody

PB9118

Polyclonal

Rabbit IgG polyclonal antibody for Transcription factor AP-2-alpha(TFAP2A) detection. Tested with WB in Human;Rat.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, rat

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

WB: The detection limit for AP2 alpha is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

E.coli-derived human AP2 alpha recombinant protein (Position: M1-G166). Human AP2 alpha shares 98% amino acid (aa) sequence identity with both mouse and rat AP2 alpha.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

TFAP2A, also known as AP-2alpha or BOFS, is a protein that in humans is encoded by the TFAP2A gene. It is mapped to 6p24.3. The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. TFAP2A acts as a sequence-specific DNA-binding transcription factor recognizing and binding to the specific DNA sequence and recruiting transcription machinery. This gene is expressed in neural crest cell lineages with the highest levels of expression corresponding to early neural crest cells, suggesting that TFAP2A plays a role in their differentiation and development.

1. Williams T, Tjian R (April 1991). "Analysis of the DNA-binding and activation properties of the human transcription factor AP-2". Genes & Development 5 (4): 670–82. 2. Mitchell PJ, Wang C, Tjian R (September 1987). "Positive and negative regulation of transcription in vitro: enhancer-binding protein AP-2 is inhibited by SV40 T antigen". Cell 50 (6): 847–61. 3. Williams T, Admon A, Lüscher B, Tjian R (December 1988). "Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements". Genes & Development 2 (12A): 1557–69. 4. Le Douarin NM, Ziller C, Couly GF (September 1993). "Patterning of neural crest derivatives in the avian embryo: in vivo and in vitro studies". Developmental Biology 159 (1): 24–49.

TFAP2A

Transcription factor AP-2-alpha

transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

Activating enhancer binding protein 2 alpha antibody Activating enhancer-binding protein 2-alpha antibody Activator protein 2 antibody AP 2 transcription factor antibody AP 2alpha antibody AP-2 antibody AP-2 transcription factor antibody AP2 antibody AP2 Transcription Factor antibody AP2-alpha antibody AP2A_HUMAN antibody AP2TF antibody BOFS antibody FLJ51761 antibody TFAP 2 antibody TFAP 2A antibody TFAP2 antibody TFAP2A antibody Transcription factor AP 2 alpha (activating enhancer binding protein 2 alpha) antibody Transcription factor AP-2-alpha antibody Transcription factor AP2 alpha antibody

P05549