Anti-HMOX1 Antibody | Boster Immunoleader PB9085 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-HMOX1 Antibody

catalog :

PB9085

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

mouse

application :

western blot, immunohistochemistry - paraffin section

publications citing this reagent :

Liu M, Wang Y, Qian C, Li H. Xuebijing exerts protective effects on lung permeability leakage and lung injury by upregulating Toll-interacting protein expression in rats with sepsis. Int J Mol Med. 2014;34:1492-504 pubmed publisher

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-HMOX1 Antibody

Catalog Number :

PB9085

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Heme oxygenase 1(HMOX1) detection. Tested with WB, IHC-P in Mouse.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: mouse

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Mouse

Notes :

WB: The detection limit for HMOX1 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived mouse HMOX1 recombinant protein (Position: E2-T261). Mouse HMOX1 shares 82% and 93% amino acid (aa) sequences identity with human and rat HMOX1, respectively.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

HMOX1 (heme oxygenase (decycling) 1) is a human gene that encodes for the enzyme heme oxygenase 1. It is an essential enzyme in heme catabolism, it cleaves heme to form biliverdin. HMOX1 belongs to the heme oxygenase family. The HMOX1 gene is located on the long (q) arm of chromosome 22 at position 12.3, from base pair 34,101,636 to base pair 34,114,748. HMOX1, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. HMOX1 activity is induced by its substrate heme and by various nonheme substances.

Reference :

1. He, C. H., Gong, P., Hu, B., Stewart, D., Choi, M. E., Choi, A. M. K., Alam, J.Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein: implication for heme oxygenase-1 gene regulation. J. Biol. Chem. 276: 20858-20865, 2001. 2. Piantadosi CA, Withers CM, Bartz RR, MacGarvey NC, Fu P, Sweeney TE, Welty-Wolf KE, Suliman HB (May 2011). "Heme oxygenase-1 couples activation of mitochondrial biogenesis to anti-inflammatory cytokine expression". J. Biol. Chem.286 (18): 16374–85.

Gene Name :

HMOX1

Protein Name :

Heme oxygenase 1

Gene Full Name :

heme oxygenase (decycling) 1

Synonyms :

32 kD antibody bK286B10 antibody D8Wsu38e antibody heat shock protein 32 kD antibody heat shock protein 32kD antibody Heat shock protein antibody Heme oxygenase (decycling) 1 antibody Heme oxygenase 1 antibody Hemox antibody HMOX 1 antibody Hmox antibody HMOX1 antibody HMOX1_HUMAN antibody HO 1 antibody HO antibody HO-1 antibody HO1 antibody Hsp32 antibody

Uniprot ID :

P14901

more info or order :

Boster Immunoleader product webpage