Anti-CD23 Antibody | Boster Immunoleader PB9051 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-CD23 Antibody

catalog :

PB9051

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

mouse, rat

application :

western blot, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

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product information

Product Name :

Anti-CD23 Antibody

Catalog Number :

PB9051

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Low affinity immunoglobulin epsilon Fc receptor(FCER2) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, mouse, rat

Applications :

WB,IHC-P,IHC-F

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human, Mouse, Rat

Immunohistochemistry(Frozen Section) :

Concentration: 0.5-1μg/ml; Tested Species: Mouse

Notes :

WB: The detection limit for CD23 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived mouse CD23 recombinant protein (Position: E50-P331). Mouse CD23 shares 52% amino acid (aa) sequence identity with human CD23.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P) and IHC(F).

Background :

CD23, also known as Fc epsilon RII, or FcεRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages. As part of a mapping of multiple probes to specific bands on chromosome 19 by fluorescence in situ hybridization, the FCE2 gene was assigned to 19p13.3. CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.

Reference :

1. Lichtman AH, Abbas AK (2003). Cellular and molecular immunology. Philadelphia: Saunders. pp. 324–325. 2. Weskamp, G., Ford, J. W., Sturgill, J., Martin, S., Docherty, A. J. P., Swendeman, S., Broadway, N., Hartmann, D., Saftig, P., Umland, S., Sehara-Fujisawa, A., Black, R. A., Ludwig, A., Becherer, J. D., Conrad, D. H., Blobel, C. P.ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23.Nature Immun. 7: 1293-1298, 2006.

Gene Name :

FCER2

Protein Name :

Low affinity immunoglobulin epsilon Fc receptor

Gene Full Name :

Fc fragment of IgE, low affinity II, receptor for (CD23)

Synonyms :

Blast 2 antibody BLAST-2 antibody Blast2 antibody C type lectin domain family 4 member J antibody C-type lectin domain family 4 member J antibody C-type lectin domain family 4, member J antibody CD 23 antibody CD 23A antibody CD23 antibody CD23 antigen antibody CD23A antibody CLEC 4J antibody CLEC4J antibody Fc epsilon RII antibody Fc fragment of IgE low affinity II receptor for antibody Fc fragment of IgE, low affinity II, receptor for (CD23) antibody Fc of IgE, low affinity II, receptor for (CD23) antibody Fc receptor IgE low affinity II alpha polypeptide antibody Fc receptor, IgE, low affinity II, alpha polypeptide, isoform CRA_a antibody Fc-epsilon-RII antibody FCE 2 antibody FCE2 antibody FCER 2 antibody Fcer2 antibody FCER2_HUMAN antibody FCER2A antibody FceRII antibody IgE binding factor antibody IgE receptor lymphocyte antibody IgE-binding factor antibody IGEBF antibody Immunoglobulin E binding factor antibody Immunoglobulin E receptor, low affinity II antibody Immunoglobulin E-binding factor antibody LEUKOCYTE ANTIGEN CD23 antibody Low Affinity IgE Receptor antibody Low affinity immunoglobulin epsilon Fc receptor antibody Low affinity immunoglobulin epsilon Fc receptor membrane bound form antibody Low affinity immunoglobulin epsilon Fc receptor soluble form antibody Ly-42 antibody Ly42 antibody Lymphocyte antigen CD23 antibody Lymphocyte IgE receptor antibody MGC93219 antibody

Uniprot ID :

P20693

more info or order :

Boster Immunoleader product webpage