Anti-ARA9 Antibody | Boster Immunoleader PB9042 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-ARA9 Antibody

catalog :

PB9042

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-ARA9 Antibody

Catalog Number :

PB9042

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for AH receptor-interacting protein(AIP) detection. Tested with WB in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

WB: The detection limit for ARA9 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human ARA9 recombinant protein (Position: D91-H330). Human ARA9 shares 95% amino acid (aa) sequences identity with both mouse and rat ARA9.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

AIP, also known as, ARA9 or XAP-2, is a protein that in humans is encoded by the AIP gene. This gene is mapped to 11q13.2. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. AIP may play a positive role in aryl hydrocarbon receptor-mediated signalling possibly by influencing its receptivity for ligand and/or its nuclear targeting. It has been shown that AIP is the cellular negative regulator of the hepatitis B virus (HBV) X protein. AIP mutations may be the cause of a familial form of acromegaly, familial isolated pituitary adenoma (FIPA).

Reference :

1. Carver LA, Bradfield CA (April 1997). "Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo". J. Biol. Chem. 272(17): 11452–6. 2. Kuzhandaivelu, N., Cong, Y.-S., Inouye, C., Yang, W.-M., Seto, E. XAP2, a novel hepatitis B virus X-associated protein that inhibits X transactivation. Nucleic Acids Res. 24: 4741-4750, 1996. 3. Occhi G, Trivellin G, Ceccato F, et al. (2010). "Prevalence of AIP mutations in a large series of sporadic Italian acromegalic patients and evaluation of CDKN1B status in acromegalic patients with multiple endocrine neoplasia.". Eur. J. Endocrinol. 163 (3): 369–376.

Gene Name :

AIP

Protein Name :

AH receptor-interacting protein

Gene Full Name :

aryl hydrocarbon receptor interacting protein

Synonyms :

AH receptor interacting protein antibody AH receptor-interacting protein antibody AIP antibody AIP_HUMAN antibody ARA 9 antibody Aryl hydrocarbon receptor interacting protein antibody Aryl-hydrocarbon receptor-interacting protein antibody fa03h10 antibody FKBP 16 antibody FKBP 37 antibody FKBP16 antibody FKBP37 antibody HBV X associated protein 2 antibody HBV X associated protein antibody HBV X-associated protein 2 antibody HBVX associated protein antibody Immunophilin homolog ARA 9 antibody Immunophilin homolog ARA9 antibody SMTPHN antibody XAP 2 antibody XAP-2 antibody XAP2 antibody

Uniprot ID :

O00170

more info or order :

Boster Immunoleader product webpage