Anti-MCP4 Antibody | Boster Immunoleader PB9030 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-MCP4 Antibody

catalog :

PB9030

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot, ELISA

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-MCP4 Antibody

Catalog Number :

PB9030

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for C-C motif chemokine 13(CCL13) detection. Tested with WB, ELISA in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

WB,ELISA

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

ELISA :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

WB: The detection limit for MCP4 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human MCP4 recombinant protein (Position: Q24-T98).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Chemokine (C-C motif) ligand 13 (CCL13) is a small cytokine belonging to the CC chemokine family. Its gene is located on human chromosome 17 within a large cluster of other CC chemokines. CCL13 induces chemotaxis in monocytes, eosinophils, T lymphocytes, and basophils by binding cell surface G-protein linked chemokine receptors such as CCR2, CCR3 and CCR5. Activity of this chemokine has been implicated in allergic reactions such as asthma. CCL13 can be induced by the inflammatory cytokines interleukin-1 and TNF-alpha.

Reference :

1. Garcia-Zepeda EA, et al. Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and no allergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3. J Immunol. 1996;157:5613–5626 2. Naruse et al., A YAC contig of the human CC chemokine genes clustered on chromosome 17q11.2. Genomics. 1996, 34(2):236-40. 3. Blanpain et al., CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist. Blood. 1999, 94:1899-905. 4. Lamkhioued et al., Monocyte chemoattractant protein (MCP)-4 expression in the airways of patients with asthma. Induction in epithelial cells and mononuclear cells by proinflammatory cytokines. Am J Respir Crit Care Med. 2000, 162:723-32.

Gene Name :

CCL13

Protein Name :

C-C motif chemokine 13

Gene Full Name :

chemokine (C-C motif) ligand 13

Synonyms :

C-C motif chemokine 13 antibody CCL13 antibody CCL13_HUMAN antibody Chemokine (C C motif) ligand 13 antibody CK beta 10 antibody CK-beta-10 antibody CKb10 antibody MCP-4 antibody MGC17134 antibody Monocyte chemoattractant protein 4 antibody Monocyte chemotactic protein 4 antibody NCC 1 antibody NCC-1 antibody NCC1 antibody New CC chemokine 1 antibody SCYA13 antibody SCYL1 antibody Small inducible cytokine A13 precursor antibody Small inducible cytokine subfamily A (Cys Cys) member 13 antibody Small-inducible cytokine A13 antibody

Uniprot ID :

Q99616

more info or order :

Boster Immunoleader product webpage