Anti-MCP3 Antibody | Boster Immunoleader PB9029 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-MCP3 Antibody

catalog :

PB9029

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

mouse

application :

western blot, ELISA

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-MCP3 Antibody

Catalog Number :

PB9029

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for C-C motif chemokine 7(CCL7) detection. Tested with WB, ELISA in Mouse.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: mouse

Applications :

WB,ELISA

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse

ELISA :

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse

Notes :

WB: The detection limit for MCP3 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived mouse MCP3 recombinant protein (Position: Q24-P97). Mouse MCP3 shares 60% and 95% amino acid (aa) sequences identity with human and rat MCP3, respectively.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). It belongs to the C-C chemokine family. By fluorescence in situ hybridization, MCP3 gene is mapped to chromosome 17q11.2-q12. MCP3 was identified as a physiologic substrate of gelatinase A. Cleaved MCP3 binds to CC-chemokine receptors-1, -2, and -3, but no longer induces calcium fluxes or promotes chemotaxis, and instead acts as a general chemokine antagonist that dampens inflammation, it has been found that matrix metalloproteinases are both effectors and regulators of the inflammatory response.

Reference :

1. Ong, V. H., Evans, L. A., Shiwen, X., Fisher, I. B., Rajkumar, V., Abraham, D. J., Black, C. M., Denton, C. P.Monocyte chemoattractant protein 3 as a mediator of fibrosis: overexpression in systemic sclerosis and the type 1 tight-skin mouse.Arthritis Rheum. 48: 1979-1991, 2003. 2. McQuibban, G. A., Gong, J.-H., Tam, E. M., McCulloch, C. A. G., Clark-Lewis, I., Overall, C. M.Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3.Science 289: 1202-1206, 2000.

Gene Name :

CCL7

Protein Name :

C-C motif chemokine 7

Gene Full Name :

chemokine (C-C motif) ligand 7

Synonyms :

C-C motif chemokine 7 antibody CCL7 antibody CCL7_HUMAN antibody Chemokine CC Motif Ligand 7 antibody FIC antibody MARC antibody MCP-3 antibody MCP3 antibody Monocyte chemoattractant protein 3 antibody Monocyte chemotactic protein 3 antibody NC28 antibody RP23-350G1.4 antibody SCYA6 antibody SCYA7 antibody Small inducible cytokine A7 antibody Small-inducible cytokine A7 antibody

Uniprot ID :

Q03366

more info or order :

Boster Immunoleader product webpage