Anti-Serum Amyloid P Antibody | Boster Immunoleader PB9021 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Serum Amyloid P Antibody

catalog :

PB9021

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

rat

application :

western blot, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Availability :

info changed 20140731

Product Name :

Anti-Serum Amyloid P Antibody

Catalog Number :

PB9021

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Serum amyloid P-component(APCS) detection. Tested with WB, IHC-P in Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: rat

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Rat

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Rat

Notes :

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived rat Serum Amyloid P recombinant protein (Position: Q21-S228). Rat Serum Amyloid P shares 72% and 80% amino acid (aa) sequences identity with human and mouse Serum Amyloid P, respectively.

Contents :

Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

Amyloid P component, serum(SAP), also known as PTX2 or APCS, is the identical serum form of amyloid P component(AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". It belongs to the pentraxins family, characterised by calcium dependent ligand binding and distinctive flattened beta-jellyroll structure similar to that of the legume lectins. This gene is mapped to 1q23.2. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

Reference :

1. Cathcart ES, Shirahama T, Cohen AS (1967). "Isolation and identification of a plasma component of amyloid". Biochim. Biophy. Acta 147: 392–393. 2. "Entrez Gene: APCS amyloid P component, serum". 3. Emsley J, White HE, O'Hara BP, Oliva G, Srinivasan N, Tickle IJ, Blundell TL, Pepys MB, Wood SP (1994). "Structure of pentameric human serum amyloid P component". Nature 367 (6461): 338–45.

Gene Name :

APCS

Protein Name :

Serum amyloid P-component

Gene Full Name :

amyloid P component, serum

Synonyms :

9.5S alpha 1 glycoprotein antibody 9.5S alpha-1-glycoprotein antibody Amyloid P component serum antibody APCS antibody MGC88159 antibody Pentaxin related antibody Pentraxin 2 antibody PTX 2 antibody PTX2 antibody SAMP_HUMAN antibody SAP antibody Serum amyloid P component antibody Serum amyloid P-component(1-203) antibody

Uniprot ID :

P23680

more info or order :

Boster Immunoleader product webpage