Anti-IL18 Antibody | Boster Immunoleader PB9014 product information

product summary

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company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-IL18 Antibody

catalog :

PB9014

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

rat

application :

western blot

publications citing this reagent :

Si L, Zhang S, Gao C, Chen S, Zhao J, Cheng X. Effects of IFN-γ on IL-18 Expression in Pregnant Rats and Pregnancy Outcomes. Asian-Australas J Anim Sci. 2013;26:1399-405 pubmed publisher

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product information

Availability :

info changed 20140731

Product Name :

Anti-IL18 Antibody

Catalog Number :

PB9014

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Interleukin-18(IL18) detection. Tested with WB in Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Rat

Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived rat IL18 recombinant protein (Position: H37-S194). Rat IL18 shares 64% and 91% amino acid (aa) sequence identity with human and mouse IL18, respectively.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Interleukin (IL)-18, also called Interferon-gamma-inducing factor (IGIF), augments natural killer (NK) activity in spleen cells. The gene encodes a precursor protein of 192 amino acids and a mature protein of 157 amino acids. IL18 is a recently discovered cytokine that modulates both T helper type 1 (Th1) and Th2 responses. IL18 is a potent proinflammatory cytokine with potential atherogenic properties. It is highly expressed in the atherosclerotic plaques compared with control normal arteries and is localized mainly in plaque macrophages.

Reference :

1. Okamura, H.; Tsutsui, H.; Komatsu, T.; Yutsudo, M.; Hakura, A.; Tanimoto, T.; Torigoe, K.; Okura, T.; Nukada, Y.; Hattori, K.; Akita, K.; Namba, M.; Tanabe, F.; Konishi, K.; Fukuda, S.; Kurimoto, M. Cloning of a new cytokine that induces IFN-gamma production by T cells. Nature 378: 88-91, 1995. 2. Reddy, P.; Teshima, T.; Kukuruga, M.; Ordemann, R.; Liu, C.; Lowler, K.; Ferrara, J. L. M. Interleukin-18 regulates acute graft-versus-host disease by enhancing Fas-mediated donor T cell apoptosis. J. Exp. Med. 194: 1433-1440, 2001. 3. Mallat, Z.; Corbaz, A.; Scoazec, A.; Besnard, S.; Leseche, G.; Chvatchko, Y.; Tedgui, A. Expression of interleukin-18 in human atherosclerotic plaques and relation to plaque instability. Circulation 104: 1598-1603, 2001.

Gene Name :

IL18

Protein Name :

Interleukin-18

Gene Full Name :

interleukin 18(interferon-gamma-inducing factor)

Synonyms :

Iboctadekin antibody IFN gamma inducing factor antibody IFN-gamma-inducing factor antibody IGIF antibody IL 1 gamma antibody IL 18 antibody IL 1g antibody IL-1 gamma antibody IL-18 antibody IL1 gamma antibody IL18 antibody IL18 protein antibody IL1F4 antibody IL1g antibody IL1gamma antibody ILIF4 antibody Interferon gamma inducing factor antibody Interferon gamma-inducing factor antibody Interleukin 1 gamma antibody Interleukin 18 antibody Interleukin-1 gamma antibody Interleukin-18 antibody Interleukin18 antibody MGC12320 antibody

Uniprot ID :

P97636

more info or order :

Boster Immunoleader product webpage