product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-IL2 Antibody
catalog :
PB9013
quantity :
100 ug/vial
price :
240 USD
clonality :
polyclonal
host :
rabbit
reactivity :
rat
application :
western blot
product information
Availability :
info changed 20140731
Product Name :
Anti-IL2 Antibody
Catalog Number :
PB9013
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Interleukin-2(IL-2) detection. Tested with WB in Rat.
Price :
240 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: rat
Applications :
WB
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Rat
Notes :
Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
E.coli-derived rat IL2 recombinant protein (Position: A21-Q155). Rat IL2 shares 66% and 80% amino acid (aa) sequence identity with human and mouse IL2, respectively.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
Interleukin-2 (IL2), formerly referred to as T-cell growth factor, is a powerfully immunoregulatory lymphokine that is produced by lectin- or antigen-activated T cells. It is produced not only by mature T lymphocytes on stimulation but also constitutively by certain T-cell lymphoma cell lines. The lymphokine interleukin-2 (IL-2) is responsible for autocrine cell cycle progression and regulation of immune responses. IL-2 expression in mature thymocytes and T cells has been found to be tightly controlled by monoallelic expression. IL-2 can act as a growth hormone for both B and T lymphocytes. This gene for interleukin 2 (IL2) is assigned to chromosome 4. IL-2 is a 15.5KDa glycoprotein, consisting of 153 amino acids in precursor form and 133 amino acids in mature form.
Reference :
1. Hollander, G. A.; Zuklys, S.; Morel, C.; Mizoguchi, E.; Mobisson, K.; Simpson, S.; Terhorst, C.; Wishart, W.; Golan, D. E.; Bhan, A. K.; Burakoff, S. J. Monoallelic expression of the interleukin-2 locus. Science 279: 2118-2121, 1998. 2. Lowenthal, J. W.; Zubler, R. H.; Nabholz, M.; MacDonald, H. R. Similarities between interleukin-2 receptor number and affinity on activated B and T lymphocytes. Nature 315: 669-672, 1985. 3. Shows, T.; Eddy, R.; Haley, L.; Byers, M.; Henry, M.; Fujita, T.; Matsui, H.; Taniguchi, T. Interleukin 2 (IL2) is assigned to human chromosome 4. Somat. Cell Molec. Genet. 10: 315-318, 1984.
Gene Name :
IL2
Protein Name :
Interleukin-2
Gene Full Name :
interleukin 2
Synonyms :
Aldesleukin antibody IL 2 antibody IL-2 antibody IL2 antibody IL2_HUMAN antibody Interleukin 2 antibody Interleukin-2 antibody Interleukin2 antibody Involved in regulation of T cell clonal expansion antibody Lymphokine antibody OTTHUMP00000164090 antibody POIL2 antibody T-cell growth factor antibody TCGF antibody
Uniprot ID :
P17108
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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