Anti-IL6 Antibody | Boster Immunoleader PB9005 product information

product summary

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company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-IL6 Antibody

catalog :

PB9005

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

rat

application :

western blot

publications citing this reagent :

Li C, Chen X, Zhang N, Song Y, Mu Y. Gastrodin inhibits neuroinflammation in rotenone-induced Parkinson's disease model rats. Neural Regen Res. 2012;7:325-31 pubmed publisher
Wang T, Zhou Y, Chen X, Zhu A. Putative role of ischemic postconditioning in a rat model of limb ischemia and reperfusion: involvement of hypoxia-inducible factor-1α expression. Braz J Med Biol Res. 2014;47:738-45 pubmed

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product information

Availability :

info changed 20140731

Product Name :

Anti-IL6 Antibody

Catalog Number :

PB9005

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for interleukin 6 (interferon, beta 2)(IL6) detection. Tested with WB in Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Rat

Notes :

WB: The detection limit for IL6 is approximately 5ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived rat IL6 recombinant protein (Position: F25-T211). Rat IL6 shares 86% amino acid (aa) sequence identity with mouse IL6.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Interleukin-6 (IL-6) is a protein that in humans is encoded by the IL6 gene. IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. IL-6 is one of the most important mediators of fever and of the acute phase response. IL-6 is also essential for hybridoma growth and is found in many supplemental cloning media such as briclone. Bowcock et al. (1988) assigned the IL6 gene to chromosome 7p21. By in situ hybridization and Southern blot analysis of mouse-human hybrid cell lines, Sutherland et al. (1988) mapped the IL-6 gene to chromosome 7p15.

Reference :

1. Ferguson-Smith AC, Chen YF, Newman MS, May LT, Sehgal PB, Ruddle FH (April 1988). "Regional localization of the interferon-beta 2/B-cell stimulatory factor 2/hepatocyte stimulating factor gene to human chromosome 7p15-p21".

Gene Name :

IL6

Protein Name :

Interleukin-6

Gene Full Name :

interleukin 6 (interferon, beta 2)

Synonyms :

Interleukin BSF 2 antibody B cell differentiation factor antibody B cell stimulatory factor 2 antibody B-cell stimulatory factor 2 antibody BSF 2 antibody BSF-2 antibody BSF2 antibody CDF antibody CTL differentiation factor antibody Cytotoxic T cell differentiation factor antibody Hepatocyte stimulating factor antibody HGF antibody HPGF antibody HSF antibody Hybridoma growth factor antibody Hybridoma growth factor Interferon beta-2 antibody Hybridoma plasmacytoma growth factor antibody IFN-beta-2 antibody IFNB2 antibody IL 6 antibody IL-6 antibody IL6 antibody IL6 protein antibody Interferon beta 2 antibody Interferon beta-2 antibody Interleukin 6(interferon beta 2) antibody Interleukin 6 antibody Interleukin-6 antibody Interleukin6 antibody

Uniprot ID :

P20607

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