Anti-TRPC4 Antibody | Boster Immunoleader PA2307 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-TRPC4 Antibody

catalog :

PA2307

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-TRPC4 Antibody

Catalog Number :

PA2307

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Short transient receptor potential channel 4(TRPC4) detection. Tested with WB in Human.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human TRPC4(961-977aa LNLPDTVTHEDYVTTRL).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

The short transient receptor potential channel 4(TRPC4), also known as Trp-related protein 4, is a protein that in humans is encoded by the TRPC4 gene. TRPC4 is a member of the transient receptor potential cation channels. It is mapped to 13q13.3. This protein forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors andtyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. TRPC4 also has an essential role in endothelial-dependent regulation of vascular tone, endothelial permeability, and neurotransmitter release from thalamic interneurons.

Reference :

1. "Entrez Gene: transient receptor potential cation channel, subfamily C, member 4" 2. Freichel, M., Vennekens, R., Olausson, J., Hoffmann, M., Muller, C., Stolz, S., Scheunemann, J., Weissgerber, P., Flockerzi, V. Functional role of TRPC proteins in vivo: lessons from TRPC-deficient mouse models. Biochem. Biophys. Res. Commun. 322: 1352-1358, 2004. 3. Zhu X, Jiang M, Peyton M, Boulay G, Hurst R, Stefani E, Birnbaumer L (May 1996). "trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry". Cell 85 (5): 661–71.

Gene Name :

TRPC4

Protein Name :

Short transient receptor potential channel 4

Gene Full Name :

transient receptor potential cation channel, subfamily C, member 4

Synonyms :

CCE1 antibody HTRP 4 antibody hTrp-4 antibody HTRP4 antibody MGC119570 antibody MGC119571 antibody MGC119572 antibody MGC119573 antibody RP11-10M8.1 antibody Short transient receptor potential channel 4 antibody STRPC4 antibody Transient receptor potential 4 antibody transient receptor potential cation channel subfamily C antibody Transient receptor potential cation channel subfamily C member 4 antibody transient receptor potential channel 4 antibody TRP 4 antibody trp related protein 4 antibody Trp-related protein 4 antibody TRP4 antibody TRPC 4 antibody TrpC4 antibody TRPC4 protein antibody TRPC4_HUMAN antibody

Uniprot ID :

Q9UBN4

more info or order :

Boster Immunoleader product webpage