Anti-p75 NGF Receptor Antibody | Boster Immunoleader PA2304 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-p75 NGF Receptor Antibody

catalog :

PA2304

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

publications citing this reagent :

Fan Z, Shen Y, Zhang F, Zuo B, Lu Q, Wu P, et al. Control of olfactory ensheathing cell behaviors by electrospun silk fibroin fibers. Cell Transplant. 2013;22:S39-50 pubmed publisher
Shen Y, Qian Y, Zhang H, Zuo B, Lu Z, Fan Z, et al. Guidance of olfactory ensheathing cell growth and migration on electrospun silk fibroin scaffolds. Cell Transplant. 2010;19:147-57 pubmed publisher

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Boster Immunoleader product webpage

product information

Product Name :

Anti-p75 NGF Receptor Antibody

Catalog Number :

PA2304

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 16(NGFR) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, mouse Predicted to work with: rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse; Predicted Species: Rat

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human p75 NGF Receptor(397-414aa TLDALLAALRRIQRADLV), different from the related mouse and rat sequences by one amino acid.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

The Low-Affinity Nerve Growth Factor Receptor(also called the NGFR or p75 neurotrophin receptor) is one of the two receptor types for the neurotrophins, a family of protein growth factors that stimulate neuronal cells to survive and differentiate. It is mapped to 17q21.33. Overexpression of NGFR was also found to activate the SM pathway. NGFR is a receptor for rabies virus, and it is also a coreceptor for the NOGO receptor for MAG signaling. This gene is a signaling partner for EPHAs and the EPHA/NGFR complex reverse signals can mediate axon repulsion required for guidance and mapping. NGFR is involved in activity-dependent synaptic plasticity. It has been shown to interact with PRKACB, FSCN1, TRAF4, Nerve growth factor, TRAF2, NDN, NGFRAP1 and MAGEH1.

Reference :

1. Dobrowsky, R. T., Werner, M. H., Castellino, A. M., Chao, M. V., Hannun, Y. A.Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor. Science 265: 1596-1599, 1994. 2. Lim, Y.-S., McLaughlin, T., Sung, T.-C., Santiago, A., Lee, K.-F., O'Leary, D. D. M.p75(NTR) mediates ephrin-A reverse signaling required for axon repulsion and mapping. Neuron 59: 746-758, 2008. 3. Rosch, H., Schweigreiter, R., Bonhoeffer, T., Barde, Y.-A., Korte, M. The neurotrophin receptor p75(NTR) modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus. Proc. Nat. Acad. Sci. 102: 7362-7367, 2005.

Gene Name :

NGFR

Protein Name :

Tumor necrosis factor receptor superfamily member 16

Gene Full Name :

nerve growth factor receptor

Synonyms :

CD271 antibody CD271 antigen antibody Gp80 LNGFR antibody Gp80-LNGFR antibody Low affinity nerve growth factor receptor antibody Low affinity neurotrophin receptor p75NTR antibody Low affinity neurotrophin receptor p75NTR antibody Low-affinity nerve growth factor receptor antibody Nerve growth factor receptor antibody Nerve growth factor receptor TNFR superfamily member 16 antibody NGF receptor antibody NGF receptor antibody Ngfr antibody p75 ICD antibody p75 ICD antibody p75 Neurotrophin receptor antibody p75 NTR antibody p75(NTR) antibody p75NTR antibody TNFR Superfamily Member 16 antibody TNFRSF16 antibody TNR16_HUMAN antibody Tumor necrosis factor receptor superfamily member 16 antibody

Uniprot ID :

P08138

more info or order :

Boster Immunoleader product webpage