product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-KCNQ5 Antibody
catalog :
PA2300
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot
product information
Product Name :
Anti-KCNQ5 Antibody
Catalog Number :
PA2300
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Potassium voltage-gated channel subfamily KQT member 5(KCNQ5) detection. Tested with WB in Human;Mouse;Rat.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human, mouse, rat
Applications :
WB
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse, Rat
Notes :
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the C-terminus of human KCNQ5(619-633aa KLDCLLDIYQQVLRK), identical to the related mouse and rat sequences.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
Potassium voltage-gated channel subfamily KQT member 5 is a protein that in humans is encoded by the KCNQ5 gene. This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. KCNQ5 is mapped to 6q13. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. KCNQ5 has been shown to interact with KvLQT3.
Reference :
1. "Entrez Gene: KCNQ5 potassium voltage-gated channel, KQT-like subfamily, member 5" 2. Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev 57 (4): 473–508. 3. Lerche C, Scherer CR, Seebohm G, Derst C, Wei AD, Busch AE, Steinmeyer K (Aug 2000). "Molecular cloning and functional expression of KCNQ5, a potassium channel subunit that may contribute to neuronal M-current diversity". J Biol Chem 275(29): 22395–400. 4. Yus-Nájera, E; Muñoz A, Salvador N, Jensen B S, Rasmussen H B, Defelipe J, Villarroel A (2003). "Localization of KCNQ5 in the normal and epileptic human temporal neocortex and hippocampal formation". Neuroscience (United States) 120 (2): 353–64.
Gene Name :
KCNQ5
Protein Name :
Potassium voltage-gated channel subfamily KQT member 5
Gene Full Name :
potassium voltage-gated channel, KQT-like subfamily, member 5
Synonyms :
KCNQ 5 antibody KCNQ5 antibody KCNQ5_HUMAN antibody KQT like 5 antibody KQT-like 5 antibody Kv7.5 antibody OTTHUMP00000064152 antibody OTTHUMP00000064153 antibody Potassium channel alpha subunit KvLQT5 antibody Potassium channel protein antibody Potassium channel subunit alpha KvLQT5 antibody Potassium voltage gated channel KQT like subfamily member 5 antibody Potassium voltage gated channel subfamily KQT member 5 antibody Potassium voltage-gated channel subfamily KQT member 5 antibody Voltage gated potassium channel subunit Kv7.5 antibody Voltage-gated potassium channel subunit Kv7.5 antibody
Uniprot ID :
Q9NR82
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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