Anti-KCNQ2 Antibody | Boster Immunoleader PA2299 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-KCNQ2 Antibody

catalog :

PA2299

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-KCNQ2 Antibody

Catalog Number :

PA2299

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Potassium voltage-gated channel subfamily KQT member 2(KCNQ2) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: rat Predicted to work with: human, mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Rat; Predicted Species: Human, Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human KCNQ2(355-372aa DLHSTWQYYERTVTVPMY), different from the related mouse and rat sequences by one amino acid.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

KCNQ2, also called kv7.2, is a potassium channel protein coded for by the gene KCNQ2. It is mapped to 20q13.33. The KCNQ2 gene encodes a voltage-gated potassium channel that is expressed in the brain. Expression of human KCNQ2 in Xenopus laevis oocytes led to potassium-selective currents that activated slowly with depolarization. Defects in this gene are a cause of benign familial neonatal convulsions type 1(BFNC), also known as epilepsy, benign neonatal type 1(EBN1). At least five transcript variants encoding five different isoforms have been found for this gene.

Reference :

1. Biervert, C., Schroeder, B. C., Kubisch, C., Berkovic, S. F., Propping, P., Jentsch, T. J., Steinlein, O. K. A potassium channel mutation in neonatal human epilepsy. Science 279: 403-406, 1998. 2. "Entrez Gene: KCNQ2 potassium voltage-gated channel, KQT-like subfamily, member 2" 3. Heron, S. E., Cox, K., Grinton, B. E., Zuberi, S. M., Kivity, S., Afawi, Z., Straussberg, R., Berkovic, S. F., Scheffer, I. E., Mulley, J. C. Deletions or duplications in KCNQ2 can cause benign familial neonatal seizures. (Letter) J. Med. Genet. 44: 791-796, 2007.

Gene Name :

KCNQ2

Protein Name :

Potassium voltage-gated channel subfamily KQT member 2

Gene Full Name :

potassium voltage-gated channel, KQT-like subfamily, member 2

Synonyms :

BFNC antibody BFNS1 antibody EBN 1 antibody EBN antibody EBN1 antibody EIEE7 antibody ENB 1 antibody ENB1 antibody HNSPC antibody KCNA 11 antibody KCNA11 antibody KCNQ 2 antibody Kcnq2 antibody KCNQ2_HUMAN antibody KQT like 2 antibody KQT-like 2 antibody KV7.2 antibody KVEBN 1 antibody KVEBN1 antibody KvLQT 2 antibody KvLQT2 antibody Neuroblastoma specific potassium channel alpha subunit KvLQT2 antibody Neuroblastoma specific potassium channel protein antibody Neuroblastoma specific potassium channel subunit alpha antibody Neuroblastoma specific potassium channel subunit alpha KvLQT2 antibody Neuroblastoma-specific potassium channel subunit alphaKvLQT2 antibody OTTHUMP00000031681 antibody OTTHUMP00000031682 antibody OTTHUMP00000031684 antibody OTTHUMP00000031685 antibody OTTHUMP00000031686 antibody OTTHUMP00000031687 antibody OTTHUMP00000031689 antibody Potassium voltage gated channel KQT like protein 2 antibody Potassium voltage gated channel KQT like subfamily member 2 antibody Potassium voltage gated channel subfamily KQT member 2 antibody Potassium voltage-gated channel subfamily KQT member 2 antibody Voltage gated potassium channel subunit Kv7.2 antibody Voltage-gated potassium channel subunit Kv7.2 antibody

Uniprot ID :

O43526

more info or order :

Boster Immunoleader product webpage