Anti-Kv1.4 Antibody | Boster Immunoleader PA2297 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Kv1.4 Antibody

catalog :

PA2297

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Kv1.4 Antibody

Catalog Number :

PA2297

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Potassium voltage-gated channel subfamily A member 4(KCNA4) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence in the middle region of human Kv1.4(329-344aa LPEFRDDRDLVMALSA), different from the related mouse and rat sequences by one amino acid.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Potassium voltage-gated channel subfamily A member 4, also known as Kv1.4 or PCN2, is a protein that in humans is encoded by the KCNA4 gene. This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. It is mapped to 11p14.1. KCNA4 belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential. KCNA4 also contributes to the cardiac transient outward potassium current(Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential. This gene has been shown to interact with DLG4, KCNA2 and DLG1.

Reference :

1. "Entrez Gene: KCNA4 potassium voltage-gated channel, shaker-related subfamily, member 4" 2. Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev 57 (4): 473–508. 3. Philipson LH, Schaefer K, LaMendola J, Bell GI, Steiner DF (Feb 1991)."Sequence of a human fetal skeletal muscle potassium channel cDNA related to RCK4". Nucleic Acids Res 18 (23): 7160.

Gene Name :

KCNA4

Protein Name :

Potassium voltage-gated channel subfamily A member 4

Gene Full Name :

potassium voltage-gated channel, shaker-related subfamily, member 4

Synonyms :

Voltage gated K+ channel HuKII antibody cardiac potassium channel antibody fetal skeletal muscle potassium channel antibody HBK 4 antibody HBK4 antibody HK 1 antibody HK1 antibody HPCN 2 antibody HPCN2 antibody HUK II antibody HUKII antibody KCNA 4 antibody KCNA 8 antibody KCNA4 antibody KCNA4_HUMAN antibody KCNA4L antibody KCNA8 antibody kv1.4 antibody PCN 2 antibody PCN2 antibody potassium channel 2 antibody potassium channel KCNA4 antibody potassium channel protein antibody Potassium voltage gated channel shaker related subfamily member 4 antibody Potassium voltage gated channel subfamily A member 4 antibody potassium voltage-gated channel shaker-related subfamily member 4-like antibody Potassium voltage-gated channel subfamily A member 4 antibody rapidly inactivating potassium channel antibody Shaker related potassium channel Kv1.4 antibody shaker-related potassium channel Kv1.4 antibody type A potassium channel antibody Voltage gated potassium channel HBK4 antibody Voltage gated potassium channel HK1 antibody Voltage gated potassium channel subunit Kv1.4 antibody Voltage-gated K(+) channel HuKII antibody voltage-gated potassium channel antibody Voltage-gated potassium channel HBK4 antibody Voltage-gated potassium channel HK1 antibody voltage-gated potassium channel protein Kv1.4 antibody Voltage-gated potassium channel subunit Kv1.4 antibody

Uniprot ID :

P22459

more info or order :

Boster Immunoleader product webpage