Boster Immunoleader

antibody

Anti-CaV1.3 Antibody

PA2293

100 ug/vial

200 USD

polyclonal

rabbit

human, mouse, rat

Anti-CaV1.3 Antibody

PA2293

Polyclonal

Rabbit IgG polyclonal antibody for Voltage-dependent L-type calcium channel subunit alpha-1D(CACNA1D) detection. Tested with WB in Human;Mouse;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: rat Predicted to work with: human, mouse

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Rat; Predicted Species: Human, Mouse

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of human CaV1.3(2146-2161aa RDEEDLADEMICITTL), different from the related mouse and rat sequences by one amino acid.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Cav1.3, also known as the calcium channel, voltage-dependent, L type, alpha 1D subunit(CACNA1D), is a human gene. It is mapped to 3p21.1. Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Alpha-1D subunit can mediate DHP-sensitive, high voltage-activated, long-lasting calcium channel activity. CACNA1D can form L-type calcium channels with negative activation thresholds which is essential for normal auditory function and controling of cardiac pacemaker activity.

1. "Entrez Gene: CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit" 2. Platzer, J., Engel, J., Schrott-Fischer, A., Stephan, K., Bova, S., Chen, H., Zheng, H., Striessnig, J. Congenital deafness and sinoatrial node dysfunction in mice lacking class D L-type Ca(2+) channels. Cell 102: 89-97, 2000. 3. Williams, M. E., Feldman, D. H., McCue, A. F., Brenner, R., Velicelebi, G., Ellis, S. B., Harpold, M. M. Structure and functional expression of alpha-1, alpha-2, and beta subunits of a novel human neuronal calcium channel subtype. Neuron 8: 71-84, 1992.

CACNA1D

Voltage-dependent L-type calcium channel subunit alpha-1D

calcium channel, voltage-dependent, L type, alpha 1D subunit

alpha-1 polypeptide antibody CAC1D_HUMAN antibody CACH3 antibody CACN4 antibody CACNA 1D antibody CACNA1D antibody CACNL1A2 antibody Calcium channel antibody Calcium channel L type alpha 1 polypeptide isoform 2 antibody Calcium channel neuroendocrine/brain type alpha 1 subunit antibody Calcium channel voltage dependent L type alpha 1 antibody Calcium channel voltage dependent L type alpha 1D subunit antibody Cav1.3 antibody CCHL1A2 antibody isoform 2 antibody L type antibody PASNA antibody SANDD antibody Voltage dependent L type calcium channel subunit alpha 1D antibody Voltage gated calcium channel alpha 1 subunit antibody Voltage gated calcium channel alpha subunit Cav1.3 antibody Voltage gated calcium channel subunit alpha Cav1.3 antibody Voltage-dependent L-type calcium channel subunit alpha-1D antibody Voltage-gated calcium channel subunit alpha Cav1.3 antibody

Q01668