product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-Kv1.6 Antibody
catalog :
PA2271
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot
product information
Product Name :
Anti-Kv1.6 Antibody
Catalog Number :
PA2271
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Potassium voltage-gated channel subfamily A member 6(KCNA6) detection. Tested with WB in Human;Mouse;Rat.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human, mouse, rat
Applications :
WB
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse, Rat
Notes :
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the C-terminus of human Kv1.6(515-529aa TPHRAYAEKRMLTEV), identical to the related mouse and rat sequences.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
Potassium voltage-gated channel subfamily A member 6, also known as HBK2 or Kv1.6, is a protein that in humans is encoded by the KCNA6 gene. This gene is mapped to 12p13.32. KCNA6 did not contain introns. The protein encoded by this gene is a voltage-gated potassium channel subunit. Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.
Reference :
1. Albrecht B, Weber K, Pongs O (1995). "Characterization of a voltage-activated K-channel gene cluster on human chromosome 12p13.". Recept. Channels 3 (3): 213–20. 2. Grupe, A., Schroter, K. H., Ruppersberg, J. P., Stocker, M., Drewes, T., Beckh, S., Pongs, O.Cloning and expression of a human voltage-gated potassium channel: a novel member of the RCK potassium channel family. EMBO J. 9: 1749-1756, 1990.
Gene Name :
KCNA6
Protein Name :
Potassium voltage-gated channel subfamily A member 6
Gene Full Name :
potassium voltage-gated channel, shaker-related subfamily, member 6
Synonyms :
HBK 2 antibody HBK2 antibody Human brain potassium channel 2 antibody KCNA 6 antibody Kcna6 antibody Potassium voltage gated channel shaker related subfamily member 6 antibody Potassium voltage gated channel subfamily A member 6 antibody Potassium voltage-gated channel subfamily A member 6 antibody Voltage gated potassium channel protein Kv1.6 antibody Voltage gated potassium channel subunit Kv1.6 antibody Voltage-gated potassium channel HBK2 antibody Voltage-gated potassium channel subunit Kv1.6 antibody
Uniprot ID :
P17658
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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