product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-EPB41L1 Antibody
catalog :
PA2266
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot
more info or order :
product information
Product Name :
Anti-EPB41L1 Antibody
Catalog Number :
PA2266
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Band 4.1-like protein 1(EPB41L1) detection. Tested with WB in Human;Mouse;Rat.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: mouse, rat
Predicted to work with: human
Applications :
WB
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Mouse,Rat; Predicted Species:Human
Notes :
Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the C-terminus of human EPB41L1(585-604aa QDQERDTVFLKDNHLAIERK), different from the related mouse and rat sequences by one amino acid.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
Band 4.1-like protein 1 is a protein that in humans is encoded by the EPB41L1 gene. This gene is mapped to 20q11.23. It is found that a heterozygous missense mutation in the EPB41L1 gene causing nonsyndromic intellectual disability. This gene may function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases. EPB41L1 has been shown to interact with ITPR1, Dopamine receptor D2, Dopamine receptor D3, CENTG1 and Nuclear mitotic apparatus protein 1.
Reference :
1. Binda, Alicia V; Kabbani Nadine, Lin Ridwan, Levenson Robert (September 2002). "D2 and D3 dopamine receptor cell surface localization mediated by interaction with protein 4.1N". Mol. Pharmacol. (United States) 62 (3): 507–13.
2. Hamdan, F. F., Gauthier, J., Araki, Y., Lin, D.-T., Yoshizawa, Y., Higashi, K., Park, A.-R., Spiegelman, D., Dobrzeniecka, S., Piton, A., Tomitori, H., Daoud, H., and 22 others. Excess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disability. Am. J. Hum. Genet. 88: 306-316, 2011. Note: Erratum: Am. J. Hum. Genet. 88: 516 only, 2011.
3. Kim AC, Van Huffel C, Lutchman M, Chishti AH (June 1998). "Radiation hybrid mapping of EPB41L1, a novel protein 4.1 homologue, to human chromosome 20q11.2-q12". Genomics 49 (1): 165–6.
Gene Name :
EPB41L1
Protein Name :
Band 4.1-like protein 1
Gene Full Name :
erythrocyte membrane protein band 4.1-like 1
Synonyms :
4.1N antibody Band 4.1 like protein 1 antibody Band 4.1-like protein 1 antibody DKFZp686H17242 antibody EPB41L 1 antibody Epb41l1 antibody Erythrocyte membrane protein band 4.1 like 1 antibody KIAA0338 antibody MGC11072 antibody MRD11 antibody Neuron type nonerythroid protein 4.1 antibody Neuronal protein 4.1 antibody Nonerythroid protein 4.1 antibody Nonerythroid protein 4.1, neuron type antibody OTTHUMP00000030825 antibody OTTHUMP00000030826 antibody OTTHUMP00000030827 antibody OTTHUMP00000030829 antibody
Uniprot ID :
Q9H4G0
more info or order :
company information

Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com925.485.4527
headquarters: USA
Premium Provider of Antibodies and ELISA Kits
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