Boster Immunoleader

antibody

Anti-P180 Lamellar Body Protein Antibody

PA2259

100 ug/vial

200 USD

polyclonal

rabbit

human, mouse, rat

Anti-P180 Lamellar Body Protein Antibody

PA2259

Polyclonal

Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family A member 3(ABCA3) detection. Tested with WB in Human;Mouse;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, rat Predicted to work with: mouse

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the N-terminus of human P180 Lamellar Body Protein(271-288aa FTYTALTIARAVVQEKER), different from the related mouse sequence by three amino acids.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

ATP-binding cassette sub-family A member 3 is a protein that in humans is encoded by the ABCA3 gene. This protein is a member of the ABC1 subfamily. It is mapped to 16p13.3. ABCA3 is homologous to C. elegans protein ced7. Ced7 functions to translocate molecules that mediate homotypic adhesion between the cell surfaces of the dying and engulfing cells, and ABCA3 may be functionally similar to it. This gene is associated with Surfactant metabolism dysfunction type 3, and it plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol. What's more, ABCA3 is also critical for the proper formation of lamellar bodies.

1. Klugbauer N, Hofmann F (Sep 1996). "Primary structure of a novel ABC transporter with a chromosomal localization on the band encoding the multidrug resistance-associated protein". FEBS Lett 391 (1–2): 61–5. 2. Wu, Y.-C., Horvitz, H. R. The C. elegans cell corpse engulfment gene ced-7 encodes a protein similar to ABC transporters. Cell 93: 951-960, 1998. 3. Yoshida, I., Ban, N., Inagaki, N. Expression of ABCA3, a causative gene for fatal surfactant deficiency, is up-regulated by glucocorticoids in lung alveolar type II cells. Biochem. Biophys. Res. Commun. 323: 547-555, 2004.

ABCA3

ATP-binding cassette sub-family A member 3

ATP-binding cassette, sub-family A(ABC1), member 3

ABC 3 antibody ABC C antibody ABC C transporter antibody ABC transporter 3 antibody ABC-C transporter antibody ABC3 antibody ABCA 3 antibody Abca3 antibody ABCA3 protein antibody ABCC antibody ATP binding cassette 3 antibody ATP binding cassette sub family A(ABC1) member 3 antibody ATP binding cassette sub family A member 3 antibody ATP binding cassette transporter 3 antibody ATP-binding cassette 3 antibody ATP-binding cassette sub-family A member 3 antibody ATP-binding cassette transporter 3 antibody CED7. C. elegans, homolog of antibody EST111653 antibody LBM 180 antibody LBM180 antibody MGC72201 antibody SMDP3 antibody

Q99758