Anti-Reticulon 1 Antibody | Boster Immunoleader PA2255 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Reticulon 1 Antibody

catalog :

PA2255

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Reticulon 1 Antibody

Catalog Number :

PA2255

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Reticulon-1(RTN1) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: rat Predicted to work with: human, mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Rat; Predicted Species: Human, Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human Reticulon 1(121-136aa TYFTGILQKENGHVTI), different from the related mouse and rat sequences by three amino acids.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Reticulon-1, also called RTN1 or NSP, is a protein that in humans is encoded by the RTN1 gene. It is mapped to 14q23.1. This gene belongs to the family of reticulon-encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. RTN1 has been shown to interact with BCL2-like 1, UGCG and spastin which is mutated in hereditary spastic paraplegia-4.

Reference :

1. "Entrez Gene: RTN1 reticulon 1" 2. Kools PF, Roebroek AJ, Van de Velde HJ, Marynen P, Bullerdiek J, Van de Ven WJ (February 1994). "Regional mapping of the human NSP gene to chromosome region 14q21→q22 by fluorescence in situ hybridization analysis". Cytogenet Cell Genet 66 (1): 48–50. 3. Mannan, A. U., Boehm, J., Sauter, S. M., Rauber, A., Byrne, P. C., Neesen, J., Engel, W.Spastin, the most commonly mutated protein in hereditary spastic paraplegia interacts with reticulon 1 an endoplasmic reticulum protein. Neurogenetics 7: 93-103, 2006.

Gene Name :

RTN1

Protein Name :

Reticulon-1

Gene Full Name :

reticulon 1

Synonyms :

Neuroendocrine specific protein antibody Neuroendocrine-specific protein antibody NSP antibody Reticulon 1 antibody Reticulon-1 antibody RTN 1 antibody RTN1 antibody RTN1_HUMAN antibody

Uniprot ID :

Q16799

more info or order :

Boster Immunoleader product webpage