Anti-PON2 Antibody | Boster Immunoleader PA2254 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-PON2 Antibody

catalog :

PA2254

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-PON2 Antibody

Catalog Number :

PA2254

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Serum paraoxonase/arylesterase 2(PON2) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, mouse, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse, Rat

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence in the middle region of human PON2(189-203aa FLKYLETYLNLHWAN), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

PON2 is an enzyme that in humans is encoded by the PON2 gene. This gene is mapped to 7q21.3. This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones and important bacterial quorum-sensing mediators suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes.

Reference :

1. "Entrez Gene: PON2 paraoxonase 2" 2. Mochizuki H, Scherer SW, Xi T, Nickle DC, Majer M, Huizenga JJ, Tsui LC, Prochazka M (Aug 1998). "Human PON2 gene at 7q21.3: cloning, multiple mRNA forms, and missense polymorphisms in the coding sequence". Gene 213 (1–2): 149–57. 3. Primo-Parmo SL, Sorenson RC, Teiber J, La Du BN (Sep 1996). "The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family". Genomics 33 (3): 498–507.

Gene Name :

PON2

Protein Name :

Serum paraoxonase/arylesterase 2

Gene Full Name :

paraoxonase 2

Synonyms :

A esterase 2 antibody A-esterase 2 antibody Aromatic esterase 2 antibody Paraoxonase 2 antibody Paraoxonase nirs antibody PON 2 antibody PON2 antibody PON2_HUMAN antibody Serum aryldialkylphosphatase 2 antibody Serum paraoxonase/arylesterase 2 antibody

Uniprot ID :

Q15165

more info or order :

Boster Immunoleader product webpage