Anti-PDCD4 Antibody | Boster Immunoleader PA2251 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-PDCD4 Antibody

catalog :

PA2251

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-PDCD4 Antibody

Catalog Number :

PA2251

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Programmed cell death protein 4(PDCD4) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human Predicted to work with: mouse, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human; Predicted Species: Mouse, Rat

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human PDCD4(351-368aa LKELEVPHFHHELVYEAI), identical to the related mouse and rat sequences.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Programmed cell death protein 4(PDCD4) is a protein that in humans is encoded by the PDCD4 gene. It is mapped to 10q25.2. This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. It also encodes a protein localized to the nucleus in proliferating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is though to play a role in apoptosis but the specific role has not yet been determined.

Reference :

1. Azzoni, L; Zatsepina, O; Abebe, B; Bennett, IM; Kanakaraj, P; Perussia, B (1998). "Differential transcriptional regulation of CD161 and a novel gene, 197/15a, by IL-2, IL-15, and IL-12 in NK and T cells". Journal of immunology 161 (7): 3493–500. 2. Entrez Gene 27250

Gene Name :

PDCD4

Protein Name :

Programmed cell death protein 4

Gene Full Name :

programmed cell death 4(neoplastic transformation inhibitor)

Synonyms :

Death up-regulated gene protein antibody Dug antibody H731 antibody Ma3 antibody MGC33046 antibody MGC33047 antibody Neoplastic transformation inhibitor antibody Neoplastic transformation inhibitor protein antibody Nuclear antigen H731 antibody Nuclear antigen H731 like antibody Nuclear antigen H731 like protein antibody Nuclear antigen H731-like antibody OTTHUMP00000020483 antibody PDCD 4 antibody Pdcd4 antibody PDCD4_HUMAN antibody Programmed cell death 4 antibody programmed cell death 4(neoplastic transformation inhibitor) antibody Programmed cell death protein 4 antibody Protein 197/15a antibody Protein MA-3 antibody RP11 348N5.4 antibody Tis antibody Topoisomerase-inhibitor suppressed protein antibody

Uniprot ID :

Q53EL6

more info or order :

Boster Immunoleader product webpage