product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-Glutamate receptor 3 Antibody
catalog :
PA2249
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot
more info or order :
product information
Product Name :
Anti-Glutamate receptor 3 Antibody
Catalog Number :
PA2249
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Glutamate receptor 3(GRIA3) detection. Tested with WB in Human;Mouse;Rat.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: mouse, rat
Predicted to work with: human
Applications :
WB
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Mouse, Rat; Predicted Species: Human
Notes :
Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence in the middle region of human Glutamate receptor 3(394-412aa RKAGYWNEYERFVPFSDQQ), identical to the related mouse and rat sequences.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
Glutamate receptor 3 is a protein that in humans is encoded by the GRIA3 gene. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA) receptors. It is mapped to Xq25. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. In addition to that, GRIA3 has been shown to interact with GRIP1 and PICK1.
Reference :
1. "Entrez Gene: GRIA3 glutamate receptor, ionotrophic, AMPA 3"
2. Hirbec, Hélène; Perestenko Olga, Nishimune Atsushi, Meyer Guido, Nakanishi Shigetada, Henley Jeremy M, Dev Kumlesh K (May 2002). "The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs". J. Biol. Chem. (United States) 277 (18): 15221–4.
3. McNamara JO, Eubanks JH, McPherson JD, Wasmuth JJ, Evans GA, Heinemann SF (Jul 1992). "Chromosomal localization of human glutamate receptor genes". J Neurosci 12 (7): 2555–62.
Gene Name :
GRIA3
Protein Name :
Glutamate receptor 3
Gene Full Name :
glutamate receptor, ionotropic, AMPA 3
Synonyms :
AMPA 3 antibody AMPA selective glutamate receptor 3 antibody AMPA-selective glutamate receptor 3 antibody GluA3 antibody GLUK3 antibody GLUR 3 antibody GLUR C antibody GLUR K3 antibody GluR-3 antibody GluR-C antibody GluR-K3 antibody GLUR3 antibody GLURC antibody Glutamate receptor 3 antibody Glutamate receptor C antibody Glutamate Receptor Ionotrophic AMPA 3 antibody Glutamate receptor ionotropic antibody Glutamate receptor subunit 3 antibody GRIA 3 antibody Gria3 antibody GRIA3_HUMAN antibody GRM 3 antibody Ionotrophic Glutamate Receptor antibody Metabotropic glutamate receptor 3 precursor antibody mGlu 3 antibody MGLUR 3 antibody MRX94 antibody
Uniprot ID :
P42263
more info or order :
company information

Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com925.485.4527
headquarters: USA
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