Anti-SGLT1 Antibody | Boster Immunoleader PA2244 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-SGLT1 Antibody

catalog :

PA2244

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-SGLT1 Antibody

Catalog Number :

PA2244

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Sodium/glucose cotransporter 1(SLC5A1) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of mouse SGLT1(620-635aa KMTKEEEEAMKMKMTD), different from the related rat sequence by one amino acid, and from the related human sequence by two amino acids.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Sodium/glucose cotransporter 1(SLC5A1), also known as NAGT or SGLT1 is a protein that in humans is encoded by the SLC5A1 gene. This gene is mapped to 22q12.3. This gene encodes a member of the sodium-dependent glucose transporter(SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene.

Reference :

1. Margolskee, R. F., Dyer, J., Kokrashvili, Z., Salmon, K. S. H., Ilegems, E., Daly, K., Maillet, E. L., Ninomiya, Y., Mosinger, B., Shirazi-Beechey, S. P. T1R3 and gustducin in gut sense sugars to regulate expression of Na(+)-glucose cotransporter 1. Proc. Nat. Acad. Sci. 104: 15075-15080, 2007. 2. Turk, E, Wright, E. M. Membrane topology motifs in the SGLT cotransporter family. J. Membr. Biol. 159: 1-20, 1997. 3. Wright, E. M., Turk, E., Zabel, B., Mundlos, S., Dyer, J. Molecular genetics of intestinal glucose transport. J. Clin. Invest. 88: 1435-1440, 1991.

Gene Name :

SLC5A1

Protein Name :

Sodium/glucose cotransporter 1

Gene Full Name :

solute carrier family 5(sodium/glucose cotransporter), member 1

Synonyms :

D22S675 antibody High affinity sodium glucose cotransporter 1 antibody High affinity sodium glucose cotransporter antibody High affinity sodium-glucose cotransporter antibody Human Na+/glucose cotransporter 1 antibody Na(+)/glucose cotransporter 1 antibody Na+/glucose cotransporter 1 antibody NAGT antibody SC5A1_HUMAN antibody SGLT 1 antibody SGLT1 antibody SLC5A1 antibody Sodium glucose cotransporter 1 antibody Sodium/glucose cotransporter 1 antibody Solute carrier family 5(sodium/glucose cotransporter) member 1 antibody Solute carrier family 5 member 1 antibody

Uniprot ID :

P13866

more info or order :

Boster Immunoleader product webpage