Anti-EAAT4 Antibody | Boster Immunoleader PA2243 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-EAAT4 Antibody

catalog :

PA2243

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-EAAT4 Antibody

Catalog Number :

PA2243

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Excitatory amino acid transporter 4(SLC1A6) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, mouse, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse, Rat

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human EAAT4(516-533aa AAVIEHLSQRELELQEAE), identical to the related mouse and rat sequences.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Excitatory amino acid transporter 4(EAAT4), also known as Sodium-dependent glutamate/aspartate transporter is a protein that in humans is encoded by the SLC1A6 gene. This gene is mapped to 19p13.12. EAAT4 is expressed predominantly in the cerebellum, has high affinity for the excitatory amino acids L-aspartate and L-glutamate. When stimulated by these amino acids, EAAT4 conducts chloride ions. This gene seems to act as a symport by cotransporting sodium.

Reference :

1. Fairman, W. A., Vandenberg, R. J., Arriza, J. L., Kavanaugh, M. P., Amara, S. G. An excitatory amino-acid transporter with properties of a ligand-gated chloride channel. ature 375: 599-603, 1995. 2. Jackson, M., Song, W., Liu, M.-Y., Jin, L., Dykes-Hoberg, M., Lin, C. G., Bowers, W. J., Federoff, H. J., Sternweis, P. C., Rothstein, J. D. Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins. Nature 410: 89-93, 2001.

Gene Name :

SLC1A6

Protein Name :

Excitatory amino acid transporter 4

Gene Full Name :

solute carrier family 1(high affinity aspartate/glutamate transporter), member 6

Synonyms :

Excitatory amino acid transporter 4 antibody High affinity neuronal glutamate transporter antibody High-affinity neuronal glutamate transporter antibody MGC33092 antibody MGC43671 antibody Slc1a6 antibody Sodium dependent glutamate/aspartate transporter antibody Sodium-dependent glutamate/aspartate transporter antibody Solute carrier family 1(high affinity aspartate/glutamate transporter) member 6 antibody Solute carrier family 1 member 6 antibody

Uniprot ID :

P48664

more info or order :

Boster Immunoleader product webpage