Boster Immunoleader

antibody

Anti-G-protein coupled receptor 30 Antibody

PA2235

100 ug/vial

200 USD

polyclonal

rabbit

human, mouse, rat

Anti-G-protein coupled receptor 30 Antibody

PA2235

Polyclonal

Rabbit IgG polyclonal antibody for G-protein coupled estrogen receptor 1(GPER1) detection. Tested with WB in Human;Mouse;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human Predicted to work with: mouse, rat

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human; Predicted Species: Mouse, Rat

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of human G-protein coupled receptor 30(275-288aa ENVFISVHLLQRTQ), different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

G-protein coupled estrogen receptor 1(GPER1), also known as the GPR30 or CEPR is a G protein-coupled receptor that in humans is encode d by the GPER gene. This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. It is mapped to 7p22.3. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.

1. Pietras, R. J., Levin, E. R., Szego, C. M. Estrogen receptors and cell signaling. (Letter)Science 310: 51-52, 2005. 2. Revankar, C. M., Cimino, D. F., Sklar, L. A., Arterburn, J. B., Prossnitz, E. R. A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science 307: 1625-1630, 2005. 3. Takada, Y., Kato, C., Kondo, S., Korenaga, R., Ando, J. Cloning of cDNAs encoding G protein-coupled receptor expressed in human endothelial cells exposed to fluid shear stress. Biochem. Biophys. Res. Commun. 240: 737-741, 1997.

GPER1

G-protein coupled estrogen receptor 1

G protein-coupled estrogen receptor 1

CEPR antibody Chemoattractant receptor-like 2 antibody Chemokine receptor-like 2 antibody CMKRL2 antibody FEG-1 antibody Flow-induced endothelial G protein-coupled receptor antibody Flow-induced endothelial G-protein coupled receptor 1 antibody G protein-coupled receptor 30 antibody G-protein coupled estrogen receptor 1 antibody G-protein coupled receptor 30 antibody GPCR-Br antibody Gper antibody GPER_HUMAN antibody GPR30 antibody IL8-related receptor DRY12 antibody Lergu antibody LERGU2 antibody leucine rich protein in GPR30 3'UTR antibody LYGPR antibody Lymphocyte-derived G-protein coupled receptor antibody Membrane estrogen receptor antibody mER antibody MGC99678 antibody

Q99527