Anti-Dopamine D2 Receptor Antibody | Boster Immunoleader PA2234 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Dopamine D2 Receptor Antibody

catalog :

PA2234

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Dopamine D2 Receptor Antibody

Catalog Number :

PA2234

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for D(2) dopamine receptor(DRD2) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human Dopamine D2 Receptor(360-375aa RRKLSQQKEKKATQML), identical to the related rat and mouse sequences.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

Dopamine receptor D2, also known as D2R or D2DR is a protein that in humans is encoded by the DRD2 gene. DRD2 gene is mapped to 11q23.2. This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.

Reference :

1. Klein, T. A., Reuter, M., von Cramon, D. Y., Ullsperger, M. Response to comment on 'Genetically determined differences in learning from errors.' Science 321: 200-201, 2008. 2. Schaefer, A., Im, H.-I., Veno, M. T., Fowler, C. D., Min, A., Intrator, A., Kjems, J., Kenny, P. J., O'Carroll, D., Greengard, P. Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction. J. Exp. Med. 207: 1843-1851, 2010. 3. Yujnovsky, I., Hirayama, J., Doi, M., Borrelli, E., Sassone-Corsi, P. Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1. Proc. Nat. Acad. Sci. 103: 6386-6391, 2006.

Gene Name :

DRD2

Protein Name :

D(2) dopamine receptor

Gene Full Name :

dopamine receptor D2

Synonyms :

D(2) dopamine receptor antibody D2 dopamine receptor antibody D2DR antibody D2R antibody Dopamine D2 receptor antibody Dopamine receptor D2 antibody DRD 2 antibody DRD2 antibody DRD2_HUMAN antibody

Uniprot ID :

P14416

more info or order :

Boster Immunoleader product webpage