Anti-Apolipoprotein J Antibody | Boster Immunoleader PA2233 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Apolipoprotein J Antibody

catalog :

PA2233

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Apolipoprotein J Antibody

Catalog Number :

PA2233

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Clusterin(CLU) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human Apolipoprotein J(429-443aa KFMETVAEKALQEYR), different from the related rat and mouse sequences by one amino acid.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

Clusterin(apolipoprotein J) is a 75 - 80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. In humans, clusterin is encoded by the CLU gene. This protein has several synonyms: dimeric acidic glycoprotein(DAG protein), testosterone repressed prostate message-2(TRPM-2), sulfated glycoprotein-2(SGP-2) and complement lysis inhibitor(CLI). Clusterin was mapped to mouse chromosome 14. Clusterin is a ubiquitously expressed molecule though to influence a variety of processes including cell death. In the brain, it accumulates in dying neurons following seizures and hypoxic-ischemic(H-I) injury. clusterin may be a new therapeutic target to modulate non-caspase-dependent neuronal death following acute brain injury.

Reference :

1. Jones SE, Jomary C (May 2002). "Clusterin". Int. J. Biochem. Cell Biol. 34 (5): 427–431. 2. "Entrez Gene: clusterin". 3. Birkenmeier, E. H., Letts, V. A., Frankel, W. N., Magenheimer, B. S., Calvet, J. P. Sulfated glycoprotein-2 (Sgp-2) maps to mouse chromosome 14. Mammalian Genome 4: 131-132, 1993. 4. Han, B. H., DeMattos, R. B., Dugan, L. L., Kim-Han, J. S., Brendza, R. P., Fryer, J. D., Kierson, M., Cirrito, J., Quick, K., Harmony, J. A. K., Aronow, B. J., Holtzman, D. M. Clusterin contributes to caspase-3-independent brain injury following neonatal hypoxia-ischemia. Nature Med. 7: 338-343, 2001.

Gene Name :

CLU

Protein Name :

Clusterin

Gene Full Name :

clusterin

Synonyms :

40 antibody AAG 4 antibody AAG4 antibody Aging associated protein 4 antibody Aging-associated gene 4 protein antibody AI893575 antibody APO J antibody Apo-J antibody APOJ antibody ApoJalpha antibody ApoJbeta antibody Apolipoprotein J antibody ApolipoproteinJ antibody CLI antibody CLU antibody CLU1 antibody CLU2 antibody CLUS_HUMAN antibody Clusterin alpha chain antibody clusterin antibody Clusterin beta chain antibody Clusterin precursor antibody Complement associated protein SP 40 40 antibody Complement associated protein SP 40 antibody Complement associated protein SP40 antibody Complement cytolysis inhibitor a chain antibody Complement cytolysis inhibitor antibody Complement cytolysis inhibitor b chain antibody Complement lysis inhibitor antibody Complement-associated protein SP-40 antibody D14Ucla3 antibody Dimeric acid glycoprotein antibody Glycoprotein 80 antibody Glycoprotein III antibody GP80 antibody Ku70-binding protein 1 antibody KUB 1 antibody KUB1 antibody MGC24903 antibody NA1/NA2 antibody RATTRPM2B antibody SGP 2 antibody SGP2 antibody SP 40 antibody SP40 antibody Sufated glycoprotein 2 antibody Sugp-2 antibody Sulfated glycoprotein 2 antibody Testosterone repressed prostate message 2 antibody Testosterone-repressed prostate message 2 antibody TRPM 2 antibody TRPM-2 antibody TRPM2 antibody TRPM2B antibody Trpmb antibody

Uniprot ID :

P10909

more info or order :

Boster Immunoleader product webpage