Anti-PROX1 Antibody | Boster Immunoleader PA2229 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-PROX1 Antibody

catalog :

PA2229

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-PROX1 Antibody

Catalog Number :

PA2229

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Prospero homeobox protein 1(PROX1) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence in the middle region of human PROX1(346-359aa KHLAETLKQELNTA), identical to the related mouse and rat sequences.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Prospero homeobox protein 1, also called PROX1 is a protein that in humans is encoded by the PROX1 gene. This gene is mapped to 1q32.3. The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. The protein encoded by this gene is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus.

Reference :

1. Dyer, M. A., Livesey, F. J., Cepko, C. L., Oliver, G. Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina. Nature Genet. 34: 53-58, 2003. 2. Harvey, N. L., Srinivasan, R. S., Dillard, M. E., Johnson, N. C., Witte, M. H., Boyd, K., Sleeman, M. W., Oliver, G. Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity. Nature Genet. 37: 1072-1081, 2005. 3. Kazenwadel, J., Michael, M. Z., Harvey, N. L. Prox1 expression is negatively regulated by miR-181 in endothelial cells. Blood 116: 2395-2401, 2010.

Gene Name :

PROX1

Protein Name :

Prospero homeobox protein 1

Gene Full Name :

prospero homeobox 1

Synonyms :

Homeobox prospero like protein antibody Homeobox prospero-like protein antibody Homeobox prospero like protein PROX1 antibody Homeobox prospero-like protein PROX1 antibody Prospero homeobox 1 antibody Prospero homeobox protein 1 antibody Prospero related homeobox 1 antibody Prospero related homeobox 1 antibody PROX 1 antibody PROX-1 antibody PROX1 antibody PROX1_HUMAN antibody

Uniprot ID :

Q92786

more info or order :

Boster Immunoleader product webpage