Boster Immunoleader

antibody

Anti-Sumo 1 Antibody

PA2220

100 ug/vial

200 USD

polyclonal

rabbit

human, mouse, rat

Anti-Sumo 1 Antibody

PA2220

Polyclonal

Rabbit IgG polyclonal antibody for Small ubiquitin-related modifier 1(SUMO1) detection. Tested with WB in Human;Mouse;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, rat Predicted to work with: mouse

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the N-terminus of human Sumo 1(15-30aa DKKEGEYIKLKVIGQD), identical to the related mouse and rat sequences.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Small ubiquitin-related modifier 1(SUMO1), also called SMT3C or PIC1 is a protein that in humans is encoded by the SUMO1 gene. This gene is mapped to 2q33.1. This gene encodes a protein that is a member of the SUMO(small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene.

1. Alkuraya, F. S., Saadi, I., Lund, J. L., Turbe-Doan, A., Morton, C. C., Maas, R. L. SUMO1 haploinsufficiency leads to cleft lip and palate. Science 313: 1751 only, 2006. 2. Kho, C., Lee, A., Jeong, D., Oh, J. G., Chaanine, A. H., Kizana, E., Park, W. J., Hajjar, R. J. SUMO1-dependent modulation of SERCA2a in heart failure. Nature 477: 601-605, 2011. 3. Martin, S., Nishimune, A., Mellor, J. R., Henley, J. M. SUMOylation regulates kainate-receptor-mediated synaptic transmission. Nature 447: 321-325, 2007.

SUMO1

Small ubiquitin-related modifier 1

small ubiquitin-like modifier 1

GAP modifying protein 1 antibody GAP-modifying protein 1 antibody GMP 1 antibody GMP1 antibody OFC10 antibody PIC 1 antibody PIC1 antibody SENP2 antibody Sentrin 1 antibody Sentrin antibody Small ubiquitin related modifier 1 antibody Small ubiquitin-like modifier 1 antibody Small ubiquitin-related modifier 1 antibody SMT3 antibody SMT3 homolog 3 antibody SMT3 suppressor of mif two 3 homolog 1 antibody SMT3, yeast, homolog 3 antibody SMT3C antibody SMT3H3 antibody SUMO-1 antibody Sumo1 antibody SUMO1_HUMAN antibody Ubiquitin homology domain protein PIC1 antibody Ubiquitin Like 1 antibody Ubiquitin like protein SMT3C antibody Ubiquitin like protein UBL1 antibody Ubiquitin-homology domain protein PIC1 antibody Ubiquitin-like protein SMT3C antibody Ubiquitin-like protein UBL1 antibody UBL 1 antibody UBL1 antibody

P63165