Anti-Olig1 Antibody | Boster Immunoleader PA2213 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Olig1 Antibody

catalog :

PA2213

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Olig1 Antibody

Catalog Number :

PA2213

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Oligodendrocyte transcription factor 1(OLIG1) detection. Tested with WB in Human.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human Olig1(94-109aa ARPDAKEEQQQQLRRK), different from the related mouse and rat sequences by four amino acids.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Oligodendrocyte transcription factor 1(OLIG1), also known as class B basic helix-loop-helix protein 6(BHLHB6) is a protein that in humans is encoded by the OLIG1 gene. This gene is mapped to 21q22.11. This gene is a member of the oligodendrocyte lineage gene family which encodes basic helix-loop-helix transcription factors. Studies in mice show that it is coexpressed with Olig2 in neural progenitors, and has a role in the development and maturation of oligodendrocytes. OLIG1 gene promotes formation and maturation of oligodendrocytes, especially within the brain. It cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube.

Reference :

1. Arnett, H. A., Fancy, S. P. J., Alberta, J. A., Zhao, C., Plant, S. R., Kaing, S., Raine, C. S., Rowitch, D. H., Franklin, R. J. M., Stiles, C. D. bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS. Science 306: 2111-2115, 2004. 2. Lu, Q. R., Sun, T., Zhu, Z., Ma, N., Garcia, M., Stiles, C. D., Rowitch, D. H. Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection. Cell 109: 75-86, 2002. 3. Zhou, Q., Anderson, D. J. The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification. Cell 109: 61-73, 2002.

Gene Name :

OLIG1

Protein Name :

Oligodendrocyte transcription factor 1

Gene Full Name :

oligodendrocyte transcription factor 1

Synonyms :

Basic domain helix loop helix protein class B 6 antibody Basic domain helix loop helix protein class B6 antibody BHLH B6 antibody BHLHB 6 antibody BHLHB6 antibody bHLHe21 antibody Class B basic helix-loop-helix protein 6 antibody Class E basic helix-loop-helix protein 21 antibody Olig 1 antibody Olig1 antibody OLIG1_HUMAN antibody Oligo 1 antibody Oligo1 antibody Oligodendrocyte lineage transcription factor 1 antibody Oligodendrocyte specific bHLH transcription factor 1 antibody Oligodendrocyte transcription factor 1 antibody

Uniprot ID :

Q8TAK6

more info or order :

Boster Immunoleader product webpage