Boster Immunoleader

antibody

Anti-MMP24 Antibody

PA2212

100 ug/vial

200 USD

polyclonal

rabbit

human, mouse

Anti-MMP24 Antibody

PA2212

Polyclonal

Rabbit IgG polyclonal antibody for Matrix metalloproteinase-24(MMP24) detection. Tested with WB in Human;Mouse;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human Predicted to work with: mouse, rat

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human; Predicted Species: Mouse, Rat

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the N-terminus of human MMP24(208-225aa YHEIKSDRKEADIMIFFA), identical to the related mouse and rat sequences.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Matrix metalloproteinase-24, also known as MT5MMP or MMP25, is an enzyme that in humans is encoded by the MMP24 gene. Proteins of the matrix metalloproteinase(MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP(MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. This gene may be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans.

1. Kinoh, H., Hayashita, H., Kajita, M., Okada, A., Seiki, M. Assignment of the genes for membrane-type-4 matrix metalloproteinase (Mmp17, MMP17) to mouse chromosome 5, human chromosome band 12q24.3 and membrane-type-5 matrix metalloproteinase (Mmp24, MMP24) to mouse chromosome 2 and human chromosome band 20q11.2-q12, respectively, by radiation hybrid and in situ hybridization. Cytogenet. Cell Genet. 87: 97-98, 1999. 2. Llano, E., Pendas, A. M., Freije, J. P., Nakano, A., Knauper, V., Murphy, G., Lopez-Otin, C. Identification and characterization of human MT5-MMP, a new membrane-bound activator of progelatinase A overexpressed in brain tumors. Cancer Res. 59: 2570-2576, 1999.

MMP24

Matrix metalloproteinase-24

matrix metallopeptidase 24(membrane-inserted)

Matrix metallopeptidase 24(membrane inserted) antibody Matrix metallopeptidase 24 antibody Membrane type 5 matrix metalloproteinase antibody Membrane type matrix metalloproteinase 5 antibody Membrane-type matrix metalloproteinase 5 antibody Membrane-type-5 matrix metalloproteinase antibody MMP 24 antibody MMP 25 antibody MMP-24 antibody Mmp24 antibody MMP24_HUMAN antibody MMP25 antibody MT MMP5 antibody MT-MMP 5 antibody MT5 MMP antibody MT5-MMP antibody MT5MMP antibody MTMMP5 antibody Processed matrix metalloproteinase-24 antibody

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