Anti-Connexin 45/GJA7 Antibody | Boster Immunoleader PA2206 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Connexin 45/GJA7 Antibody

catalog :

PA2206

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Connexin 45/GJA7 Antibody

Catalog Number :

PA2206

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Gap junction gamma-1 protein(GJC1) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human Predicted to work with: mouse, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human; Predicted Species: Mouse, Rat

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human Connexin 45(308-322aa KIAYKQNKANTAQEQ), different from the related mouse and rat sequences by one amino acid.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Gap junction gamma-1 protein(GJC1), also known as gap junction alpha-7 protein(GJA7) or connexin 45(Cx45), is a protein that in humans is encoded by the GJC1 gene. The International Radiation Hybrid Mapping Consortium mapped the GJA7 gene to chromosome 17q21.31. This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell.

Reference :

1. Kaba, R. A., Coppen, S. R., Dupont, E., Skepper, J. N., Elneil, S., Haw, M. P., Pepper, J. R., Yacoub, M. H., Rothery, S., Severs, N. J. Comparison of connexin 43, 40 and 45 expression patterns in the developing human and mouse hearts. Cell Commun. Adhesion 8: 339-343, 2001. 2. Tsai, M.-Y., Lan, K.-C., Huang, K.-E., Huang, F.-J., Kung, F.-T., Chang, S.-Y. Significance of mRNA levels of connexin37, connexin43, and connexin45 in luteinized granulosa cells of controlled hyperstimulated follicles. Fertil. Steril. 80: 1437-1443, 2003.

Gene Name :

GJC1

Protein Name :

Gap junction gamma-1 protein

Gene Full Name :

gap junction protein, gamma 1, 45kDa

Synonyms :

Connexin 45 antibody Connexin-45 antibody Connexin45 antibody CX 31.9 antibody CX 45 antibody CX31.9 antibody Cx45 antibody CXG1_HUMAN antibody DKFZp686P0738 antibody Gap junction alpha 7 protein antibody Gap junction alpha-7 protein antibody Gap junction gamma 1 protein antibody Gap junction gamma-1 protein antibody Gap junction protein alpha 7 45kDa antibody Gap junction protein alpha 7 antibody Gap junction protein, gamma 1, 45kDa antibody GJA 7 antibody GJA7 antibody GJC1 antibody GJD3 antibody

Uniprot ID :

P36383

more info or order :

Boster Immunoleader product webpage