Anti-LI Cadherin Antibody | Boster Immunoleader PA2200 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-LI Cadherin Antibody

catalog :

PA2200

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-LI Cadherin Antibody

Catalog Number :

PA2200

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Cadherin-17(CDH17) detection. Tested with WB in Human.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human LI Cadherin(686-699aa LIFEATDDDQHLFR).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Cadherin-17, also known as HPT1 or CDH16 is a protein that in humans is encoded by the CDH17 gene. By somatic cell hybrid analysis and fluorescence in situ hybridization, CDH17 gene is mapped to 8q22.1. This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine.

Reference :

1. Dantzig, A. H., Hoskins, J., Tabas, L. B., Bright, S., Shepard, R. L., Jenkins, I. L., Duckworth, D. C., Sportsman, J. R., Mackensen, D., Rosteck, P. R., Jr., Skatrud, P. L. Association of intestinal peptide transport with a protein related to the cadherin superfamily. cience 264: 430-433, 1994. 2. Kremmidiotis, G., Baker, E., Crawford, J., Eyre, H. J., Nahmias, J., Callen, D. F. Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity. Genomics 49: 467-471, 1998.

Gene Name :

CDH17

Protein Name :

Cadherin-17

Gene Full Name :

cadherin 17, LI cadherin(liver-intestine)

Synonyms :

BILL-cadherin antibody CAD17_HUMAN antibody Cadherin 16 antibody Cadherin 17 antibody Cadherin-17 antibody CDH16 antibody CDH17 antibody FLJ26931 antibody HPT 1 antibody human peptide transporter 1 antibody Intestinal peptide-associated transporter HPT 1 antibody Intestinal peptide-associated transporter HPT-1 antibody LI-cadherin antibody Liver Cadherin antibody liver intestine cadherin antibody Liver-intestine cadherin antibody

Uniprot ID :

Q12864

more info or order :

Boster Immunoleader product webpage