Anti-SLC30A4 Antibody | Boster Immunoleader PA2191 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-SLC30A4 Antibody

catalog :

PA2191

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-SLC30A4 Antibody

Catalog Number :

PA2191

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Zinc transporter 4(SLC30A4) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human; Predicted Species: Mouse

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Rat; Predicted Species: Human, Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human SLC30A4(407-427aa TIQLQSYRQEVDRTCANCQSS), different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

Zinc transporter 4, also called SLC30A4 or ZNT4 is a protein that in humans is encoded by the SLC30A4 gene. SLC30A4, or ZNT4 belongs to the ZNT family of zinc transporters. This gene is mapped to 15q21.1. Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases, alkaline phosphatases, various dehydrogenases, and superoxide dismutases. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop.

Reference :

1. Huang, L., Kirschke, C. P., Gitschier, J. Functional characterization of a novel mammalian zinc transporter, ZnT6. J. Biol. Chem. 277: 26389-26395, 2002. 2. Seve, M., Chimienti, F., Devergnas, S., Favier, A. In silico identification and expression of SLC30 family genes: an expressed sequence tag data mining strategy for the characterization of zinc transporters' tissue expression. BMC Genomics 5: 32, 2004.

Gene Name :

SLC30A4

Protein Name :

Zinc transporter 4

Gene Full Name :

solute carrier family 30(zinc transporter), member 4

Synonyms :

Dri 27 protein antibody Lethal milk protein antibody Slc30a4 antibody Solute carrier family 30(zinc transporter), member 4 antibody Solute carrier family 30 member 4 antibody Zinc transporter 4 antibody ZnT-4 antibody Znt4 antibody ZNT4_HUMAN antibody

Uniprot ID :

O14863

more info or order :

Boster Immunoleader product webpage