Boster Immunoleader

antibody

Anti-Monocarboxylic acid transporter 1 Antibody

PA2188

100 ug/vial

200 USD

polyclonal

rabbit

western blot, immunohistochemistry - paraffin section

Anti-Monocarboxylic acid transporter 1 Antibody

PA2188

Polyclonal

Rabbit IgG polyclonal antibody for Monocarboxylate transporter 1(SLC16A1) detection. Tested with WB, IHC-P in Human.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB,IHC-P

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Concentration: 0.5-1μg/ml; Tested Species: Human

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence in the middle region of human Monocarboxylic acid transporter 1(236-254aa RHPKQEKRSVFQTINQFLD).

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Monocarboxylate transporter 1, also called SLC16A1 or MCT1 is a protein that in humans is encoded by the SLC16A1 gene. This gene is mapped to 1p13.2. This gene acts as Proton-linked monocarboxylate transporter. It catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.

1. Birsoy, K., Wang, T., Possemato, R., Yilmaz, O. H., Koch, C. E., Chen, W. W., Hutchins, A. W., Gultekin, Y., Peterson, T. R., Carette, J. E., Brummelkamp, T. R., Clish, C. B., Sabatini, D. M. MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors. Nature Genet. 45: 104-108, 2013. 2. Lee, Y., Morrison, B. M., Li, Y., Lengacher, S., Farah, M. H., Hoffman, P. N., Liu, Y., Tsingalia, A., Jin, L., Zhang, P.-W., Pellerin, L., Magistretti, P. J., Rothstein, J. D.Oligodendroglia metabolically support axons and contribute to neurodegeneration.Nature 487: 443-448, 2012.

SLC16A1

Monocarboxylate transporter 1

solute carrier family 16, member 1(monocarboxylic acid transporter 1)

FLJ36745 antibody HHF7 antibody MCT 1 antibody MCT antibody MGC44475 antibody Monocarboxylate transporter 1 antibody monocarboxylate transporter antibody Monocarboxylate transporter isoform 1 antibody Monocarboxylic acid transporter 1 antibody SLC16A1 antibody SLC16A1 protein antibody Solute carrier family 16(monocarboxylic acid transporters) member 1 antibody Solute carrier family 16 member 1(monocarboxylic acid transporter 1) antibody Solute carrier family 16 member 1 antibody

P53985