Boster Immunoleader

antibody

Anti-SLC12A6 Antibody

PA2171

100 ug/vial

200 USD

polyclonal

rabbit

human, mouse, rat

Anti-SLC12A6 Antibody

PA2171

Polyclonal

Rabbit IgG polyclonal antibody for Solute carrier family 12 member 6(SLC12A6) detection. Tested with WB in Human;Mouse;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human Predicted to work with: mouse, rat

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human; Predicted Species: Mouse, Rat

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of human SLC12A6(1060-1080aa QKAKSMEGFQDLLNMRPDQSN), different from the related mouse and rat sequences by one amino acid.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Solute carrier family 12(potassium/chloride transporters), member 6, also called SLC12A6 or KCC3, is a protein that in humans is encoded by the SLC12A6 gene. This gene is a member of the K-Cl cotransporter(KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. By radiation hybrid and somatic cell hybrid analyses, this gene is mapped to 15q14. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.

1. Howard, H. C., Mount, D. B., Rochefort, D., Byun, N., Dupre, N., Lu, J., Fan, X., Song, L., Riviere, J.-B., Prevost, C., Horst, J., Simonati, A., and 12 others. The K-Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosum. Nature Genet. 32: 384-392, 2002. Note: Erratum: Nature Genet. 32: 681 only, 2002. 2. Salin-Cantegrel, A., Riviere, J.-B., Shekarabi, M., Rasheed, S., DaCal, S., Laganiere, J., Gaudet, R., Rochefort, D., Lesca, G., Gaspar, C., Dion, P. A., Lapointe, J.-Y., Rouleau, G. A.Transit defect of potassium-chloride co-transporter 3 is a major pathogenic mechanism in hereditary motor and sensory neuropathy with agenesis of the corpus callosum. J. Biol. Chem. 286: 28456-28465, 2011.

SLC12A6

Solute carrier family 12 member 6

solute carrier family 12(potassium/chloride transporters), member 6

ACCPN antibody Furosemide sensitive KCl cotransporter 3 antibody Gaxp antibody KCC 3 antibody KCC 3A antibody KCC 3B antibody KCC3 A antibody KCC3 antibody KCC3 B antibody KCC3A antibody KCC3B antibody Potassium chloride cotransporter 3 antibody Potassium chloride cotransporter KCC3a S3 antibody SLC12 A6 antibody SLC12A 6 antibody Solute carrier family 12(potassium/chloride transporters), member 6 antibody Solute carrier family 12, member 6 antibody

Q9UHW9