Anti-GLUT12 Antibody | Boster Immunoleader PA2167 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-GLUT12 Antibody

catalog :

PA2167

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-GLUT12 Antibody

Catalog Number :

PA2167

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 12(SLC2A12) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence in the middle region of human GLUT12(256-272aa SLKDEYQYSFWDLFRSK), identical to the related mouse and rat sequences.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Solute carrier family 2, facilitated glucose transporter member 12, also known as SLC2A12, is a protein that in humans is encoded by the SLC2A12 gene. SLC2A12 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion. This family of transporters shows conservation of 12 transmembrane helices as well as functionally significant amino acid residues. By genomic sequence analysis, this gene is mapped to chromosome 6q23.2. SLC2A12 was detected in a perinuclear location in MCF7 cells in the absence of insulin; however, SLC2A12 redistributed to the plasma membrane of MCF7 cells grown continuously in the presence of insulin. This gene acts as facilitative glucose transporter.

Reference :

1. Linden, K. C., DeHaan, C. L., Zhang, Y., Glowacka, S., Cox, A. J., Kelly, D. J., Rogers, S.Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of hypertension and diabetic nephropathy. Am. J. Physiol. Renal Physiol. 290: F205-F213, 2006. 2. Wood, I. S., Hunter, L., Trayhurn, P. Expression of class III facilitative glucose transporter genes (GLUT-10 and GLUT-12) in mouse and human adipose tissues. Biochem. Biophys. Res. Commun. 308: 43-49, 2003.

Gene Name :

SLC2A12

Protein Name :

Solute carrier family 2, facilitated glucose transporter member 12

Gene Full Name :

solute carrier family 2(facilitated glucose transporter), member 12

Synonyms :

Glucose transporter type 12 antibody GLUT 12 antibody GLUT-12 antibody GLUT12 antibody GLUT8 antibody GTR12_HUMAN antibody SLC2A12 antibody Solute carrier family 2(facilitated glucose transporter) member 12 antibody Solute carrier family 2 facilitated glucose transporter member 12 antibody Solute carrier family 2 member 12 antibody Solute carrier family 2, facilitated glucose transporter member 12 antibody

Uniprot ID :

Q8TD20

more info or order :

Boster Immunoleader product webpage