Boster Immunoleader

antibody

Anti-Glucose Transporter 8 Antibody

PA2165

100 ug/vial

200 USD

polyclonal

rabbit

human, mouse, rat

western blot, immunohistochemistry - paraffin section

info changed 20150327

Anti-Glucose Transporter 8 Antibody

PA2165

Polyclonal

Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 8(SLC2A8) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, rat Predicted to work with: mouse

WB,IHC-P

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Concentration: 0.5-1μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of mouse Glucose Transporter 8(461-477aa ETKGRTLEQVTAHFEGR), different from the related rat sequence by one amino acid, and from the related human sequence by two amino acids.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Solute carrier family 2, facilitated glucose transporter member 8, also known as SLC2A8, is the eighth member of glucose transporter superfamily. It is characterized by the presence of two leucine residues in its N-terminal intracellular domain, which influences intracellular trafficking. This gene is mapped to 9q33.3. Based on sequence comparison, the glucose transporters are grouped into three classes and this gene is a member of class II. It may act as the insulin-regulated facilitative glucose transporter. This gene binds cytochalasin B in a glucose-inhibitable manner. The binds seems to be a dual-specific sugar transporter as it is inhibitable by fructose.

1. Carayannopoulos, M. O., Chi, M. M.-Y., Cui, Y., Pingsterhaus, J. M., McKnight, R. A., Mueckler, M., Devaskar, S. U., Moley, K. H. GLUT8 is a glucose transporter responsible for insulin-stimulated glucose uptake in the blastocyst. Proc. Nat. Acad. Sci. 97: 7313-7318, 2000. 2. Ibberson, M., Uldry, M., Thorens, B. GLUTX1, a novel mammalian glucose transporter expressed in the central nervous system and insulin-sensitive tissues. J. Biol. Chem. 275: 4607-4612, 2000.

SLC2A8

Solute carrier family 2, facilitated glucose transporter member 8

solute carrier family 2(facilitated glucose transporter), member 8

Glucose transporter type 8 antibody Glucose transporter type X1 antibody GLUT8 antibody GLUTX1 antibody solute carrier family 2(facilitated glucose transporter) member 8 antibody

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