Boster Immunoleader

antibody

Anti-EAAT3 Antibody

PA2164-2

100 ug/vial

200 USD

polyclonal

rabbit

mouse, rat

Anti-EAAT3 Antibody

PA2164-2

Polyclonal

Rabbit IgG polyclonal antibody for Excitatory amino acid transporter 3(SLC1A1) detection. Tested with WB in Mouse;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: mouse, rat

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse, Rat

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the N-terminus of mouse EAAT3(10-27aa DWRRFLRNHWLLLSTVAA), identical to the related rat sequence.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Solute carrier family 1 member 1, also called SLC1A1, is a protein that in humans is encoded by the SLC1A1 gene. By Southern analysis of a panel of human/rodent somatic cell hybrids and by fluorescence in situ hybridization(FISH), this gene is mapped to 9p24.2. This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are though to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect.

1. Berman, A. E., Chan, W. Y., Brennan, A. M., Reyes, R. C., Adler, B. L., Suh, S. W., Kauppinen, T. M., Edling, Y., Swanson, R. A. N-acetylcysteine prevents loss of dopaminergic neurons in the EAAC1-/- mouse. Ann. Neurol. 69: 509-520, 2011. 2. Myles-Worsley, M., Tiobech, J., Browning, S. R., Korn, J., Goodman, S., Gentile, K., Melhem, N., Byerley, W., Faraone, S. V., Middleton, F. A. Deletion at the SLC1A1 glutamate transporter gene co-segregates with schizophrenia and bipolar schizoaffective disorder in a 5-generation family. Am. J. Med. Genet. 162B: 87-95, 2013.

SLC1A1

Excitatory amino acid transporter 3

solute carrier family 1(neuronal/epithelial high affinity glutamate transporter, system Xag), member 1

EAA3_HUMAN antibody EAAC 1 antibody EAAC1 antibody EAAT 3 antibody Excitatory amino acid carrier 1 antibody Excitatory amino acid carrier1 antibody Excitatory amino acid transporter 3 antibody Excitatory amino acid transporter3 antibody Excitatory amino-acid carrier 1 antibody GLUTAMATE TRANSPORTER, HIGH-AFFINITY antibody MEAAC 1 antibody MEAAC1 antibody Neuronal and epithelial glutamate transporter antibody REAAC 1 antibody REAAC1 antibody Slc1 a1 antibody Slc1a 1 antibody SLC1A1 antibody Sodium dependent glutamate/aspartate transporter 3 antibody Sodium-dependent glutamate/aspartate transporter 3 antibody Solute carrier family 1(neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 antibody SOLUTE CARRIER FAMILY 1(NEURONAL/EPITHELIAL HIGH AFFINITY GLUTAMATE TRANSPORTER), MEMBER 1 antibody Solute carrier family 1(neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 antibody Solute carrier family 1 member 1 antibody Solute carrier family 1, member 1 antibody

P51906