product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-Fibulin 2 Antibody
catalog :
PA2159
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot
product information
Product Name :
Anti-Fibulin 2 Antibody
Catalog Number :
PA2159
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Fibulin-2(FBLN2) detection. Tested with WB in Human;Mouse;Rat.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human, rat Predicted to work with: mouse
Applications :
WB
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse
Notes :
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the N-terminus of human Fibulin 2(188-205aa DPERHYEDPYSYDQEVAE), different from the related mouse and rat sequences by two amino acids.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
Fibulin-2, also known as FBLN2, is a protein that in humans is encoded by the FBLN2 gene. This gene encodes an extracellular matrix protein, which belongs to the fibulin family. By isotopic in situ hybridization, this gene is mapped to 3p25.1. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. It may play a role in testis development. Its binding to fibronectin and some other ligands is calcium dependent.
Reference :
1. Ackerman, C., Locke, A. E., Feingold, E., Reshey, B., Espana, K., Thusberg, J., Mooney, S., Bean, L. J. H., Dooley, K. J., Cua, C. L., Reeves, R. H., Sherman, S. L., Maslen, C. L. An excess of deleterious variants in VEGF-A pathway genes in Down-syndrome-associated atrioventricular septal defects. Am. J. Hum. Genet. 91: 646-659, 2012. 2. Kuivaniemi, H., Marshall, A., Ganguly, A., Chu, M.-L., Abbott, W. M., Tromp, G. Fibulin-2 exhibits high degree of variability, but no structural changes concordant with abdominal aortic aneurysms. Europ. J. Hum. Genet. 6: 642-646, 1998.
Gene Name :
FBLN2
Protein Name :
Fibulin-2
Gene Full Name :
fibulin 2
Synonyms :
Fbln2 antibody FBLN2_HUMAN antibody FIBL-2 antibody Fibulin-2 antibody OTTHUMP00000216670 antibody OTTHUMP00000216671 antibody OTTHUMP00000216672 antibody
Uniprot ID :
P98095
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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