Anti-EIF2S2 Antibody | Boster Immunoleader PA2157 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-EIF2S2 Antibody

catalog :

PA2157

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-EIF2S2 Antibody

Catalog Number :

PA2157

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Eukaryotic translation initiation factor 2 subunit 2(EIF2S2) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human Predicted to work with: mouse, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human; Predicted Species: Mouse, Rat

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human EIF2S2(199-214aa FQAVTGKRAQLRAKAN), identical to the related mouse and rat sequences.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Eukaryotic translation initiation factor 2 subunit 2, also called EIF2S2 is a protein that in humans is encoded by the EIF2S2 gene. This gene belongs to the EIF-2-beta family. EIF2S2 is mapped to 20q11.2. Eukaryotic translation initiation factor 2(EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation.

Reference :

1. Heaney, J. D., Michelson, M. V., Youngren, K. K., Lam, M.-Y. J., Nadeau, J. H. Deletion of eIF2beta suppresses testicular cancer incidence and causes recessive lethality in agouti-yellow mice. Hum. Molec. Genet. 18: 1395-1404, 2009. 2. Jennings, M. D., Pavitt, G. D. eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation. Nature 465: 378-381, 2010. Note: Erratum: Nature 468: 122 only, 2010.

Gene Name :

EIF2S2

Protein Name :

Eukaryotic translation initiation factor 2 subunit 2

Gene Full Name :

eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa

Synonyms :

DKFZp686L18198 antibody eIF 2 beta antibody eIF-2-beta antibody EIF2 antibody EIF2B antibody EIF2beta antibody EIF2S2 antibody Eukaryotic initiation factor 2 beta antibody eukaryotic initiation factor 2-beta antibody Eukaryotic translation initiation factor 2 beta antibody Eukaryotic translation initiation factor 2 subunit 2 antibody Eukaryotic translation initiation factor 2 subunit 2 beta 38kDa antibody Eukaryotic translation initiation factor 2 subunit 2 beta antibody Eukaryotic translation initiation factor 2 subunit beta antibody eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa antibody IF2B_HUMAN antibody MGC8508 antibody PPP1R67 antibody protein phosphatase 1, regulatory subunit 67 antibody

Uniprot ID :

P20042

more info or order :

Boster Immunoleader product webpage