Anti-P2X6 Antibody | Boster Immunoleader PA2128 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-P2X6 Antibody

catalog :

PA2128

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-P2X6 Antibody

Catalog Number :

PA2128

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for P2X purinoceptor 6(P2RX6) detection. Tested with WB in Human.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human P2X6(387-406aa VWRELALASQARLAECLRRS).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Purinergic receptor P2X-Like 1, also known as P2X6, is a protein that in humans is encoded by the P2RX6 gene. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. This gene belongs to the family of P2X receptors. P2RXL1 gene was mapped to chromosome 22q11 by fluorescence in situ hybridization. This gene is a receptor for ATP that acts as a ligand-gated ion channel. It can mediate rapid and selective permeability to cations.

Reference :

1. Collo, G., North, R. A., Kawashima, E., Merlo-Pich, E., Neidhart, S., Surprenant, A., Buell, G. Cloning of P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels. J. Neurosci. 16: 2495-2507, 1996. 2. Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP, et al. (Dec 1999). "The DNA sequence of human chromosome 22".Nature 402 (6761): 489–95. 3. Urano, T., Nishimori, H., Han, H., Furuhata, T., Kimura, Y., Nakamura, Y., Tokino, T.Cloning of P2XM, a novel human P2X receptor gene regulated by p53. Cancer Res. 57: 3281-3287, 1997.

Gene Name :

P2RX6

Protein Name :

P2X purinoceptor 6

Gene Full Name :

purinergic receptor P2X, ligand-gated ion channel, 6

Synonyms :

ATP receptor antibody P2RX6 antibody P2RX6_HUMAN antibody P2RXL1 antibody P2X purinoceptor 6 antibody P2X6 antibody P2XM antibody Purinergic receptor antibody Purinergic receptor P2X ligand gated ion channel 6 antibody Purinergic receptor P2X like 1 antibody Purinergic receptor P2X-like 1 antibody Purinoceptor P2X6 antibody Purinoreceptor P2X6 antibody Skeletal muscle expressed P2X antibody

Uniprot ID :

O15547

more info or order :

Boster Immunoleader product webpage